Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001.

Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001.
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DOI:
10.1038/sj.bjc.6601696
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发表时间:
2004-04-05
影响因子:
8.8
通讯作者:
--
中科院分区:
医学1区
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--
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我们研究了20世纪90年代英格兰和威尔士癌症存活率的国家趋势和社会经济不平等,使用了220万名患者的基于人口的数据,这些患者在1986年至1999年期间被诊断为20种最常见的癌症之一,并跟踪到2001年。患者在确诊时根据他们居住的选区的特点被分配到五种剥夺类别中的一种(从“富裕”到“剥夺”)。我们估计了诊断后5年的相对存活率,根据年龄、性别和历期分别调整了每种剥夺类别的背景死亡率。我们估计了1986-90年、1991-95年和1996-99年期间的存活率趋势和不同剥夺类别之间的存活率差异(“剥夺差距”)。我们使用周期分析来检查不久的将来可能的存活率。在20世纪90年代,男女大多数癌症的存活率都有所提高,而且在不久的将来,大多数癌症的存活率可能会继续提高。与上世纪80年代末相比,上世纪90年代末确诊的患者的贫富存活率差距更大。20世纪90年代英格兰和威尔士癌症存活率的增加被证明与生存中不断扩大的剥夺差距显著相关。
We examined national trends and socioeconomic inequalities in cancer survival in England and Wales during the 1990s, using population-based data on 2.2 million patients who were diagnosed with one of the 20 most common cancers between 1986 and 1999 and followed up to 2001. Patients were assigned to one of five deprivation categories (from ‘affluent’ to ‘deprived’) using characteristics of their electoral ward of residence at diagnosis. We estimated relative survival up to 5 years after diagnosis, adjusting separately in each deprivation category for background mortality by age, sex and calendar period. We estimated trends in survival and in the difference in survival between deprivation categories (‘deprivation gap’) over the periods 1986–90, 1991–95 and 1996–99. We used period analysis to examine likely survival rates in the near future. Survival improved for most cancers in both sexes during the 1990s, and appears likely to continue improving for most cancers in the near future. The deprivation gap in survival between rich and poor was wider for patients diagnosed in the late 1990s than in the late 1980s. Increases in cancer survival in England and Wales during the 1990s are shown to be significantly associated with a widening deprivation gap in survival.
DOI: 10.1016/s0302-2838(03)00085-x
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