Shear modulus imaging with spatially-modulated ultrasound radiation force.
Shear modulus imaging with spatially-modulated ultrasound radiation force.
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DOI：
10.1177/016173460903100401
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发表时间：
2009-10
影响因子：
2.3
通讯作者：
Elegbe E
中科院分区：
文献类型：
--
作者：
McAleavey S;Menon M;Elegbe E
空间调制超声辐射力(S-MURF)在组织模拟体模和猪肝脏中应用于剪切模数成像。扫描和数据采集采用西门子Antares超声扫描仪和VF7-3线阵，工作频率为4.21 MHz。切变模数分别为5.1kPa和12.4kPa时，Zerdine™均匀模体的模数估计值的标准偏差均在平均值的6%以内。Zerdine球体直径为1厘米(标称为2.7、4.7和15 kpa)，背景为8千帕(标称)，清晰可分辨。基于明胶的体模中软锥形包裹体的横截面图像显示空间分辨率约为2.5 mm。猪肝组织体外标本的剪切模量值平均值为3kPa.用0.5毫升10%的戊二醛引起的硬性损伤清晰可见，其剪切模量值超过10千帕。与戊二醛的扩散有关的模数梯度是可见的。检查了两个脉冲序列，仅在用于产生横波的波束的定时上不同。给出了波束序列和后续信号处理的详细信息。
The application of Spatially Modulated Ultrasound Radiation Force (SMURF) to shear modulus imaging is demonstrated in tissue mimicking phantoms and porcine liver. Scanning and data acquisition was performed with a Siemens Antares ultrasound scanner and VF7-3 linear array operating at 4.21 MHz. Modulus estimates in uniform phantoms of Zerdine™ with shear moduli of 5.1 and 12.4 kPa exhibited standard deviations within 6% of the mean value. Zerdine spheres 1 cm in diameter (nominally 2.7, 4.7, and 15 kPa) in a 8 kPa (nominal) background are clearly resolved. Cross sectional images of a soft conical inclusion in a gelatin-based phantom indicate a spatial resolution of approximately 2.5 mm. Images of the shear modulus of an ex-vivo sample of porcine liver tissue show an average value of 3kPa. A stiff lesion induced with 0.5 mL of 10% glutaraldehyde is clearly visible as a region of shear modulus in excess of 10 kPa. A modulus gradient associated with the diffusion of the glutaraldehyde is visible. Two pulse sequences were examined, differing only in the timing of the beams used to generate the shear waves. Details of the beam sequences and subsequent signal processing are presented.
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影响因子：
2.3
作者：
McAleavey, Stephen;Collins, Erin;Menon, Manoj
通讯作者：
Menon, Manoj
DOI：
10.1109/t-su.1985.31615
发表时间：
1985-01-01
期刊：
IEEE TRANSACTIONS ON SONICS AND ULTRASONICS
影响因子：
--
作者：
KASAI, C;NAMEKAWA, K;OMOTO, R
通讯作者：
OMOTO, R
影响因子：
2.9
作者：
Sarvazyan, AP;Rudenko, OV;Emelianov, SY
通讯作者：
Emelianov, SY
影响因子：
2.9
作者：
Palmeri, M. L.;Wang, M. H.;Nightingale, K. R.
通讯作者：
Nightingale, K. R.
影响因子：
2.9
作者：
PARKER, KJ
通讯作者：
PARKER, KJ