SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review.
SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review.
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DOI：
10.1016/j.ijbiomac.2021.08.076
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发表时间：
2021-10-01
影响因子：
8.2
通讯作者：
Kafil HS
中科院分区：
文献类型：
--
作者：
Fathizadeh H;Afshar S;Masoudi MR;Gholizadeh P;Asgharzadeh M;Ganbarov K;Köse Ş;Yousefi M;Kafil HS
全球感染新冠肺炎疫情已经一年多了，死亡率仍然很高。除了需要通过使用口罩和保持社交距离等非药物措施尽量减少病毒传播外，正在作出许多努力，开发各种疫苗，以在全世界预防这种疾病。到目前为止，有几种疫苗已经在临床试验的各个阶段达到了安全性和有效性的最后阶段，其中一些疫苗，如Moderna/NIAID和BioNTech/辉瑞，已经报告了非常高的安全性和保护性。重要的一点是，比较不同的疫苗并不容易，因为没有衡量中和作用的既定标准。在本研究中，我们回顾了COVID-19疫苗的常用平台，并试图呈现这些疫苗有效性的最新报告。
The world has been suffering from COVID-19 disease for more than a year, and it still has a high mortality rate. In addition to the need to minimize transmission of the virus through non-pharmacological measures such as the use of masks and social distance, many efforts are being made to develop a variety of vaccines to prevent the disease worldwide. So far, several vaccines have reached the final stages of safety and efficacy in various phases of clinical trials, and some, such as Moderna/NIAID and BioNTech/Pfizer, have reported very high safety and protection. The important point is that comparing different vaccines is not easy because there is no set standard for measuring neutralization. In this study, we have reviewed the common platforms of COVID-19 vaccines and tried to present the latest reports on the effectiveness of these vaccines.
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影响因子：
3.1
作者：
Darnell ME;Subbarao K;Feinstone SM;Taylor DR
通讯作者：
Taylor DR
影响因子：
16.1
作者：
Batty CJ;Heise MT;Bachelder EM;Ainslie KM
通讯作者：
Ainslie KM
影响因子：
5.5
作者：
Dey A;Chozhavel Rajanathan TM;Chandra H;Pericherla HPR;Kumar S;Choonia HS;Bajpai M;Singh AK;Sinha A;Saini G;Dalal P;Vandriwala S;Raheem MA;Divate RD;Navlani NL;Sharma V;Parikh A;Prasath S;Sankar Rao M;Maithal K
通讯作者：
Maithal K
DOI：
10.1056/nejmoa2035389
发表时间：
2021-02-04
期刊：
The New England journal of medicine
影响因子：
--
作者：
Baden LR;El Sahly HM;Essink B;Kotloff K;Frey S;Novak R;Diemert D;Spector SA;Rouphael N;Creech CB;McGettigan J;Khetan S;Segall N;Solis J;Brosz A;Fierro C;Schwartz H;Neuzil K;Corey L;Gilbert P;Janes H;Follmann D;Marovich M;Mascola J;Polakowski L;Ledgerwood J;Graham BS;Bennett H;Pajon R;Knightly C;Leav B;Deng W;Zhou H;Han S;Ivarsson M;Miller J;Zaks T;COVE Study Group
通讯作者：
COVE Study Group
影响因子：
3.7
作者：
Bisht H;Roberts A;Vogel L;Subbarao K;Moss B
通讯作者：
Moss B