Sensing cellular stress through STIM proteins.
Sensing cellular stress through STIM proteins.
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DOI:
10.1038/nchembio.619
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发表时间:
2011-07-18
影响因子:
14.8
通讯作者:
Gill, Donald L.
中科院分区:
文献类型:
--
作者:
Soboloff, Jonathan;Madesh, Muniswamy;Gill, Donald L.
In response to decreasing Ca2+ levels in the endoplasmic reticulum, STIM proteins couple with Orai channels in the plasma membrane, leading to Ca2+ influx into the cell. In addition to Ca2+-related endoplasmic reticulum stress, STIM proteins are emerging as general stress sensors that react to multiple stress signals to orchestrate Ca2+ signaling and homeostasis.
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影响因子:
64.5
作者:
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DOI:
10.1083/jcb.200505022
发表时间:
2005-09-26
期刊:
The Journal of cell biology
影响因子:
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