A community health worker and mobile health app intervention to improve adherence to HIV medication among persons with HIV: the CHAMPS study protocol.
A community health worker and mobile health app intervention to improve adherence to HIV medication among persons with HIV: the CHAMPS study protocol.
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DOI:
10.1186/s12889-023-15616-9
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发表时间:
2023-05-24
影响因子:
4.5
通讯作者:
中科院分区:
文献类型:
--
作者:
Persons with HIV (PWH) can now achieve a near-normal life expectancy due to antiretroviral therapy (ART). Despite widespread availability of ART in the United States (US), many of the country’s approximate 1.1 million PWH are not achieving viral suppression due to poor ART adherence. Viral suppression rates are particularly low in Alabama (AL, 62%) and New York City (NYC, 67%). There is mixed evidence on the efficacy of community health workers (CHW) and mHealth interventions for improving ART adherence and viral suppression in PWH thus, we sought to combine these interventions and test the efficacy for improving health outcomes in PWH. The CHAMPS study is a two-arm randomized controlled trial among 300 PWH with suboptimal primary care appointment adherence (n = 150 in AL and 150 in NYC) over the course of 12 months. Participants are randomly assigned to CHAMPS (intervention) or a standard-of-care (control) arm. Participants in the intervention arm are given a CleverCap pill bottle that syncs to the WiseApp to track medication adherence, reminds users to take their medication at a set time, and enables communication with CHW. All participants complete baseline, 6-month, and 12-month follow-up visits where surveys are administered and, CD4 and HIV-1 viral load are obtained through blood draw. Maintaining ART adherence has significant implications in HIV management and transmission. mHealth technologies have been shown to optimize the provision of health services, produce positive changes in health behavior, and significantly improve health outcomes. CHW interventions also provide personal support to PWH. The combination of these strategies may provide the necessary intensity to increase ART adherence and clinic attendance among PWH at highest risk for low engagement. Delivering care remotely enables CHW to contact, assess, and support numerous participants throughout the day, reducing burden on CHW and potentially improving intervention durability for PWH. The adoption of the WiseApp coupled with community health worker sessions in the CHAMPS study has the potential to improve HIV health outcomes, and will add to the growing knowledge of mHealth and CHW efforts to improve PWH medication adherence and viral suppression. This trial was registered with Clinicaltrials.gov (NCT04562649) on 9/24/20.
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影响因子:
3.7
作者:
Adam GP;Di M;Cu-Uvin S;Halladay C;Smith BT;Iyer S;Trikalinos TA
通讯作者:
Trikalinos TA
DOI:
10.1080/09540120500038058
发表时间:
2005-08-01
影响因子:
1.7
作者:
Amico, KR;Toro-Alfonso, J;Fisher, JD
通讯作者:
Fisher, JD
DOI:
10.3390/e20030168
发表时间:
2018-03-05
期刊:
Entropy (Basel, Switzerland)
影响因子:
--
作者:
Guo X;Zhang C
通讯作者:
Zhang C
影响因子:
3.7
作者:
Badawy, Sherif M.;Radovic, Ana
通讯作者:
Radovic, Ana
影响因子:
0.9
作者:
Antognini, Alessandro Baldi
通讯作者:
Antognini, Alessandro Baldi