Accelerating cardiac cine MRI using a deep learning-based ESPIRiT reconstruction.

Accelerating cardiac cine MRI using a deep learning-based ESPIRiT reconstruction.
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DOI:
10.1002/mrm.28420
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发表时间:
2021-01
影响因子:
3.3
通讯作者:
Cheng JY
Cheng JY
中科院分区:
医学3区
文献类型:
--
作者:
Sandino CM;Lai P;Vasanawala SS;Cheng JY

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To propose a novel combined parallel imaging and deep learning-based reconstruction framework for robust reconstruction of highly accelerated 2D cardiac cine MRI data. We propose DL-ESPIRiT, an unrolled neural network architecture that utilizes an extended coil sensitivity model to address SENSE-related field-of-view (FOV) limitations in previously proposed deep learning-based reconstruction frameworks. Additionally, we propose a novel neural network design based on (2+1)D spatiotemporal convolutions to produce more accurate dynamic MRI reconstructions than conventional 3D convolutions. The network is trained on fully-sampled 2D cardiac cine datasets collected from eleven healthy volunteers with IRB approval. DL-ESPIRiT is compared against a state-of-the-art parallel imaging and compressed sensing method known as l1-ESPIRiT. The reconstruction accuracy of both methods is evaluated on retrospectively undersampled datasets (R=12) with respect to standard image quality metrics as well as automatic deep learning-based segmentations of left ventricular volumes. Feasibility of DL-ESPIRiT is demonstrated on two prospectively undersampled datasets acquired in a single heartbeat per slice. The (2+1)D DL-ESPIRiT method produces higher fidelity image reconstructions when compared to l1-ESPIRiT reconstructions with respect to standard image quality metrics (P <0.001). As a result of improved image quality, segmentations made from (2+1)D DL-ESPIRiT images are also more accurate than segmentations from l1-ESPIRiT images. DL-ESPIRiT synergistically combines a robust parallel imaging model and deep learning-based priors to produce high-fidelity reconstructions of retrospectively undersampled 2D cardiac cine data acquired with reduced FOV. Although a proof-of-concept is shown, further experiments are necessary to determine the efficacy of DL-ESPIRiT in prospectively undersampled data.
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