Melanoma: linked temporal and latitude changes in the United States
Melanoma: linked temporal and latitude changes in the United States
复制标题
黑色素瘤：美国的时间和纬度变化相关
作者：
John A. H. Lee;J. Scotto
The rise in the incidence and mortality from melanoma of the skin is slowing down in younger age groups in the United States. In many White populations, including that of the US, melanoma incidence and mortality rates increase according to proximity of residence to the Equator. Variations with age in this gradient do not seem to have been examined. We examined how the influence of latitude on melanoma rates varied with age. Estimates of age-specific trends by time and by latitude for natural logarithm (Ln) melanoma incidence-rates from the Surveillance, Epidemiology and End Results (SEER) programs, and Ln melanoma mortality rates from the US Vital Statistics were derived from fitted regression equations. Unexpectedly, a decline from old age to youth in the influence of latitude was found for both incidence and mortality from melanoma of the skin in males, and for mortality in females. Further, these changes in the relationship to latitude with age correlated with the changes in time trends with age. The link with exposure suggests that the time trends in melanoma are driven by variations in damage to melanocytes in early life that increases sensitivity to sunlight. This has implications for the general understanding of melanoma etiology and for health education.
肺炎衣原体菌株 TWAR、肺炎支原体以及大学生健康诊所人群中急性呼吸道疾病的病毒感染。
影响因子：
5
作者：
Thom,DH;Grayston,JT;Wang,SP;Kuo,CC;Altman,J
通讯作者：
Altman,J
马萨诸塞州皮肤恶性黑色素瘤的系统性漏报。
影响因子：
13.8
作者：
Koh,HK;Clapp,RW;Barnett,JM;Nannery,WM;Tahan,SR;Geller,AC;Bhawan,J;Harrist,TJ;Kwan,T;Stadecker,M
通讯作者：
Stadecker,M