Current State of Breast Cancer Diagnosis, Treatment, and Theranostics.
Current State of Breast Cancer Diagnosis, Treatment, and Theranostics.
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DOI：
10.3390/pharmaceutics13050723
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发表时间：
2021-05-14
期刊：
影响因子：
5.4
通讯作者：
Menon JU
中科院分区：
文献类型：
--
作者：
Bhushan A;Gonsalves A;Menon JU
乳腺癌是全世界妇女癌症相关发病率和死亡率的主要原因之一。所有类型癌症的早期诊断和有效治疗对于积极的预后至关重要。在诊断时肿瘤尺寸较小的患者具有显著更高的存活率和显著降低的癌症致命概率。因此，许多新的技术正在开发用于早期检测原发性肿瘤，以及远处转移和复发性疾病，以有效地管理乳腺癌。治疗诊断学已经成为同时诊断、成像和治疗癌症的新范式。它有可能通过个性化治疗提供及时且更好的患者护理。在纳米治疗诊断中，细胞特异性靶向部分、成像剂和治疗剂可以嵌入单一制剂中以进行有效治疗。在这篇综述中，我们将重点介绍乳腺癌管理的不同诊断技术和治疗策略，并探讨乳腺癌治疗诊断学的最新进展。我们的主要重点将是总结最近的研究论文和专利中报道的乳腺癌诊断和治疗的最新趋势和技术，并讨论有效的乳腺癌治疗的未来前景。
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial for a positive prognosis. Patients with small tumor sizes at the time of their diagnosis have a significantly higher survival rate and a significantly reduced probability of the cancer being fatal. Therefore, many novel technologies are being developed for early detection of primary tumors, as well as distant metastases and recurrent disease, for effective breast cancer management. Theranostics has emerged as a new paradigm for the simultaneous diagnosis, imaging, and treatment of cancers. It has the potential to provide timely and improved patient care via personalized therapy. In nanotheranostics, cell-specific targeting moieties, imaging agents, and therapeutic agents can be embedded within a single formulation for effective treatment. In this review, we will highlight the different diagnosis techniques and treatment strategies for breast cancer management and explore recent advances in breast cancer theranostics. Our main focus will be to summarize recent trends and technologies in breast cancer diagnosis and treatment as reported in recent research papers and patents and discuss future perspectives for effective breast cancer therapy.
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影响因子：
14
作者：
Burke, Andrew R.;Singh, Ravi N.;Carroll, David L.;Wood, James C. S.;D'Agostino, Ralph B., Jr.;Ajayan, Pulickel M.;Torti, Frank M.;Torti, Suzy V.
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Torti, Suzy V.
影响因子：
4.7
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影响因子：
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作者：
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通讯作者：
Jakubowicz, Jerzy
影响因子：
5.9
作者：
Baltzer, Pascal;Mann, Ritse M.;Le Bihan, Denis
通讯作者：
Le Bihan, Denis
影响因子：
2.8
作者：
Beser, Ash Rehber;Tuzlali, Sitki;Dalay, Nejat
通讯作者：
Dalay, Nejat