Effect of Density of Hydroxyapatite Fiber Material on Bone Regeneration in Vertical Bone Augmentation Model

Effect of Density of Hydroxyapatite Fiber Material on Bone Regeneration in Vertical Bone Augmentation Model
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羟基磷灰石纤维材料密度对垂直骨增量模型骨再生的影响

DOI:
10.11223/jarde.10.115
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发表时间:
2013
期刊:
Journal of oral tissue engineering
影响因子:
--
通讯作者:
S. Kasugai
S. Kasugai
中科院分区:
--
文献类型:
--
作者:
Masaki Fujii;M. Shiota;Kanako Noritake;Kazuhiro Kon;Hitoshi Sato;S. Kasugai

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本研究的目的是比较不同密度的可生物降解羟基磷灰石纤维(HAf)材料对垂直骨增量的影响。使用十只雄性日本白兔。充满不同HAf密度(称为“低”、“中”、“高”或“空”)的聚四氟乙烯室被固定在颅骨上。 12周后,对动物实施安乐死。使用微型计算机断层扫描对标本进行放射学分析并进行组织学检查。在中等密度组中,新骨量最高。目前的结果表明这种材料作为骨替代品的潜力以及材料密度在其应用中的重要性。
The purpose of this study was to compare the effects of different densities of biodegradable hydroxyapatite fiber (HAf) material on vertical bone augmentation. Ten male Japanese white rabbits were used. Polytetrafluoroethylene chambers, which were filled with different HAf densities (termed ‘low’,‘intermediate’,‘high’or ‘empty’), were fixed to the calvarial bone. After 12weeks, animals were euthanized. Specimens were radiologically analyzed with micro-computed tomography and histologically examined. In the intermediate-density group the new bone volume was the highest. The present results suggest the potentiality of this material as bone substitute and the importance of material density in its application.
DOI: 10.1016/j.biomaterials.2006.06.013
发表时间: 2007-01-01
期刊: BIOMATERIALS
影响因子: 14
作者:
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通讯作者: Ma, Peter X.
DOI: 10.1089/107632702753503045
发表时间: 2002-02-01
期刊: TISSUE ENGINEERING
影响因子: --
作者:
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通讯作者: Mooney, DJ
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期刊: BIOMATERIALS
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