Advances in neurocognitive rehabilitation research from 1992 to 2017: The ascension of neural plasticity.

Advances in neurocognitive rehabilitation research from 1992 to 2017: The ascension of neural plasticity.
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DOI:
10.1037/neu0000396
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发表时间:
2017-11
期刊:
影响因子:
2.4
通讯作者:
Tran SM
Tran SM
中科院分区:
心理学3区
文献类型:
--
作者:
Crosson B;Hampstead BM;Krishnamurthy LC;Krishnamurthy V;McGregor KM;Nocera JR;Roberts S;Rodriguez AD;Tran SM

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在过去的25年里,神经认知康复已经发生了深刻的变化,并将继续推动其发展。虽然神经系统可塑性的概念被讨论过,但直到1992年之后,基于经验的可塑性的基础才达到严重影响康复研究的临界经验质量。这篇综述的目的是描述神经可塑性的出现如何改变了神经认知康复研究。重要的发展包括(a)引入一种广泛可用的工具来测量大脑可塑性(即fMRI), (b)开发新的结构成像技术,可以定义神经可塑性的限制和机会,(c)部署非侵入性脑刺激来利用神经可塑性进行康复,(d)表明运动对神经可塑性有积极影响的文献的增长,特别是对老年人。(e)通过创造超越治疗活动界限的干预措施来增强神经可塑性。鉴于大量的文献,这些领域中的每一个都是通过实例来发展的。神经可塑性的影响日益扩大,为神经损伤和神经障碍的神经认知康复提供了新的模型和工具,也为神经可塑性的测量和预测其局限性和机会提供了新的方法。早期临床试验提供了非常令人鼓舞的结果。现在神经可塑性已经站稳了脚跟,它将在未来25年继续影响神经认知康复研究的发展,推动神经损伤和疾病的康复。
The past 25 years have seen profound changes in neurocognitive rehabilitation and that continue to motivate its evolution. Although the concept of nervous system plasticity was discussed by, the foundation for experience-based plasticity had not reached the critical empirical mass to seriously impact rehabilitation research until after 1992. The objective of this review is to describe how the emergence of neural plasticity has changed neurocognitive rehabilitation research. The important developments included (a) introduction of a widely available tool that could measure brain plasticity (i.e., fMRI), (b) development of new structural imaging techniques that could define limits of and opportunities for neural plasticity, (c) deployment of non-invasive brain stimulation to leverage neural plasticity for rehabilitation, (d) growth of a literature indicating that exercise has positively impacts neural plasticity, especially for older persons, and (e) enhancement neural plasticity by creating interventions that generalize beyond the boundaries of treatment activities. Given the massive literature, each of these areas is developed by example. The expanding influence of neural plasticity has provided new models and tools for neurocognitive rehabilitation in neural injuries and disorders, as well as methods for measuring neural plasticity and predicting its limits and opportunities. Early clinical trials have provided very encouraging results. Now that neural plasticity has gained a firm foothold, it will continue to influence the evolution of neurocognitive rehabilitation research for the next 25 years and advance rehabilitation for neural injuries and disease.
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