Hydrostatic pressure as a driver of cell and tissue morphogenesis.
Hydrostatic pressure as a driver of cell and tissue morphogenesis.
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DOI:
10.1016/j.semcdb.2022.04.021
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发表时间:
2022-11
影响因子:
7.3
通讯作者:
Megason, Sean G.
中科院分区:
文献类型:
--
作者:
Chugh, Mayank;Munjal, Akankshi;Megason, Sean G.
关键词:
Morphogenesis, the process by which tissues develop into functional shapes, requires coordinated mechanical forces. Most current literature ascribes contractile forces derived from actomyosin networks as the major driver of tissue morphogenesis. Recent works from diverse species have shown that pressure derived from fluids can generate deformations necessary for tissue morphogenesis. In this review, we discuss how hydrostatic pressure is generated at the cellular and tissue level and how the pressure can cause deformations. We highlight and review findings demonstrating the mechanical roles of pressures from fluid-filled lumens and viscous gel-like components of the extracellular matrix. We also emphasise the interactions and mechanochemical feedbacks between extracellular pressures and tissue behaviour in driving tissue remodelling. Lastly, we offer perspectives on the open questions in the field that will further our understanding to uncover new principles of tissue organisation during development.
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影响因子:
2.7
作者:
DESMOND, ME;JACOBSON, AG
通讯作者:
JACOBSON, AG
影响因子:
64.8
作者:
通讯作者:
--
DOI:
10.1085/jgp.48.1.15
发表时间:
1964-09
期刊:
The Journal of general physiology
影响因子:
--
作者:
DIAMOND JM
通讯作者:
DIAMOND JM
影响因子:
64.8
作者:
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通讯作者:
Hiiragi, Takashi
影响因子:
64.8
作者:
Charras, GT;Yarrow, JC;Mitchison, TJ
通讯作者:
Mitchison, TJ