Obstructive sleep apnea screening in pregnancy, perinatal outcomes, and impact of maternal obesity.
Obstructive sleep apnea screening in pregnancy, perinatal outcomes, and impact of maternal obesity.
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DOI：
10.1055/s-0031-1276740
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发表时间：
2011-09
影响因子：
2
通讯作者：
Aagaard-Tillery K
中科院分区：
文献类型：
--
作者：
Olivarez SA;Ferres M;Antony K;Mattewal A;Maheshwari B;Sangi-Haghpeykar H;Aagaard-Tillery K
这项前瞻性观察性研究探讨了妊娠期高血压疾病和小于胎龄儿 (SGA) 与阻塞性睡眠呼吸暂停 (OSA) 的关系，这是通过 OSA 筛查措施和睡眠研究确定的。两项基于症状的筛查问卷，即柏林问卷 (BQ) 和 Epworth 嗜睡量表 (ESS)，纳入了 1509 名孕妇。筛查呈阳性的受试者被转介进行多导睡眠图（PSG）检查。主要结局是妊娠高血压或先兆子痫的发生。 [a1]广义线性模型（GLM）用于估计关联的相对风险。 1157 名受试者可用于结果分析。 BQ 筛查呈阳性与 GLM 模型中的高血压疾病呈正相关（aRR=1.90，95%CI 1.52-2.37）。在这项大型前瞻性试验中，GLM 模型表明，BQ 而不是 ESS 与测量的不良妊娠结局存在显着相关性，并且特定项目比其他项目更好地预测这些结果。然而，不能假设 BQ 与 OSA 存在因果关系。
This prospective observational study explored the association of hypertensive disorders of pregnancy and small-for-gestational age (SGA) with obstructive sleep apnea (OSA) as determined by screening measures for OSA and sleep studies. Two symptom-based screening questionnaires, the Berlin Questionnaire (BQ) and the Epworth Sleepiness Scale (ESS), were administered to enroll 1509 gravidae. Screen positive subjects were referred for polysomnography (PSG). The primary outcome was the occurrence of either gestational hypertension or preeclampsia. [a1]Generalized linear models (GLM) were used to estimate the relative risks of associations. 1157 subjects were available for outcomes analysis. Screening positive on the BQ was positively associated with hypertensive disorders in GLM models (aRR=1.90, 95%CI 1.52–2.37). In this large prospective trial, GLM modeling suggest that the BQ but not the ESS demonstrated significant association with measured adverse pregnancy outcomes, and specific items predicted these outcomes better than others. However, causative association of BQ with OSA cannot be assumed.
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影响因子：
9.8
作者：
Bukowski, R;Gahn, D;Saade, G
通讯作者：
Saade, G
影响因子：
9.6
作者：
Loube, DI;Poceta, JS;Mitler, MM
通讯作者：
Mitler, MM
影响因子：
4.4
作者：
Johns, MW
通讯作者：
Johns, MW
DOI：
10.1046/j.1365-2281.1998.00114.x
发表时间：
1998-07-01
期刊：
CLINICAL PHYSIOLOGY
影响因子：
--
作者：
Kansanen, M;Vanninen, E;Uusitupa, M
通讯作者：
Uusitupa, M
DOI：
10.1016/j.ijgo.2007.08.012
发表时间：
2008-02-01
影响因子：
3.8
作者：
Sahin, Figen Kir;Koken, Gulengul;Unlu, Mehmet
通讯作者：
Unlu, Mehmet