Atrial conduction velocity mapping: clinical tools, algorithms and approaches for understanding the arrhythmogenic substrate.

Atrial conduction velocity mapping: clinical tools, algorithms and approaches for understanding the arrhythmogenic substrate.
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DOI:
10.1007/s11517-022-02621-0
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发表时间:
2022-09
影响因子:
3.2
通讯作者:
--
中科院分区:
工程技术3区
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表征患者特定的心房传导特性对于理解心律失常的驱动因素、预测潜在的心律失常途径和个性化治疗方法非常重要。表征心肌基质健康状况的一个指标是心房传导速度,它描述了电波阵面在心肌中传播的速度和方向。心房传导速度标测算法在研究实验室和工业中都在不断开发中。在这篇评论文章中,我们对目前发表的不同类别的计算CV的方法进行了广泛的概述,并从整体上洞察了它们的不同优点和缺点。我们将技术分为局部方法、全局方法和逆方法,并从它们对生物物理学的忠实性、结合不确定量化以及它们考虑心房流形的能力方面进行了讨论。
Characterizing patient-specific atrial conduction properties is important for understanding arrhythmia drivers, for predicting potential arrhythmia pathways, and for personalising treatment approaches. One metric that characterizes the health of the myocardial substrate is atrial conduction velocity, which describes the speed and direction of propagation of the electrical wavefront through the myocardium. Atrial conduction velocity mapping algorithms are under continuous development in research laboratories and in industry. In this review article, we give a broad overview of different categories of currently published methods for calculating CV, and give insight into their different advantages and disadvantages overall. We classify techniques into local, global, and inverse methods, and discuss these techniques with respect to their faithfulness to the biophysics, incorporation of uncertainty quantification, and their ability to take account of the atrial manifold.
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