How early do parent concerns predict later autism diagnosis?
How early do parent concerns predict later autism diagnosis?
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DOI：
10.1097/dbp.0b013e3181ba0fcf
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发表时间：
2009-10
期刊：
影响因子：
--
通讯作者：
Sigman M
中科院分区：
文献类型：
--
作者：
Ozonoff S;Young GS;Steinfeld MB;Hill MM;Cook I;Hutman T;Macari S;Rogers SJ;Sigman M
研究父母对生命第一年半发育的担忧与后来的自闭症诊断结果之间的关系。采用前瞻性纵向设计，收集了自闭症高风险和低风险婴儿的家长对发育的担忧。家长被问及研究入学时以及婴儿 6、12 和 18 个月时的发育问题。然后对婴儿进行随访直至 36 个月，然后确定诊断状态。当孩子 12 个月大时，有一个患有自闭症的大孩子的父母比有典型结局的孩子的父母对自闭症谱系障碍相关领域的担忧要多得多。这些担忧与发育状态和自闭症症状的独立测量显着相关，并有助于预测哪些婴儿后来会被诊断出患有自闭症或自闭症谱系障碍。然而，在 6 个月大时，患有自闭症的大孩子的父母的担忧并不能很好地预测结果。根据美国儿科学会的建议，明确探究家长对发育的担忧有助于识别需要更密切监测和监视的儿童。
To study the relationship between parent concerns about development in the first year and a half of life and later autism diagnostic outcomes. Parent concerns about development were collected for infants at high and low risk for autism, using a prospective, longitudinal design. Parents were asked about developmental concerns at study intake and when their infant was 6, 12, and 18 months. Infants were then followed up until 36 months, when diagnostic status was determined. By the time their child was 12 months, parents who have an older child with autism reported significantly more concerns in autism spectrum disorders-related areas than parents of children with typical outcomes. These concerns were significantly related to independent measures of developmental status and autism symptoms and helped predict which infants would later be diagnosed with autism or autism spectrum disorders. At 6 months, however, the concerns of parents who have an older child with autism do not predict outcome well. Explicitly probing for parent concerns about development is useful for identifying children in need of closer monitoring and surveillance, as recommended by the American Academy of Pediatrics.
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DOI：
10.1111/j.1469-7610.2006.01531.x
发表时间：
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影响因子：
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