A Monte Carlo-based model for steady-state diffuse reflectance spectrometry in human skin: estimation of carbon monoxide concentration in livor mortis
A Monte Carlo-based model for steady-state diffuse reflectance spectrometry in human skin: estimation of carbon monoxide concentration in livor mortis
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基于蒙特卡罗的人体皮肤稳态漫反射光谱测定模型：尸肝中一氧化碳浓度的估计
DOI：
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
J. Honerkamp
中科院分区：
文献类型：
--
作者：
M. Bohnert;R. Walther;T. Roths;J. Honerkamp
从物理学上来说，皮肤可视为一种光学混浊介质，其中光线主要被胶原纤维、线粒体和细胞核散射，而吸收则由还原血红蛋白、氧合血红蛋白、胆红素和黑色素的含量决定。当测量几何形状和照明光谱已知时，皮肤的光学特性可以通过扩散系数和吸收系数来近似描述。这些值定义了每个波长传播的每单位距离的扩散和吸收概率。基于这些参数，借助蒙特卡罗模拟开发了数学皮肤模型。通过将一氧化碳血红蛋白 (CO-Hb) 的吸收系数应用到皮肤模型中，作者想研究该方法是否适合从动物的光谱反射曲线中确定 CO-Hb 浓度。迄今为止对 28 例一氧化碳中毒死亡事件进行的调查表明，这通常是可能的。在几乎所有情况下，实际的 CO-Hb 值都可以通过使用蒙特卡罗模拟来正确估计。
In terms of physics, the skin can be regarded as an optically turbid medium in which the light is mainly scattered by the collagen fibers, mitochondria and cell nuclei, whereas the absorption is determined by the content of reduced hemoglobin, oxyhemoglobin, bilirubin, and melanin. When the measuring geometry and the illumination spectrum are known, the optical characteristics of the skin can be approximately described by the diffusion and absorption coefficients. These values define the diffusion and absorption probability per unit distance traveled for each wavelength. Based on these parameters, a mathematical skin model was developed with the help of Monte Carlo simulations. By implementing the absorption coefficient of carbon monoxide hemoglobin (CO-Hb) into the skin model, the authors wanted to investigate whether this method is suitable to determine the CO-Hb concentration from spectral reflectance curves of livores. The investigations performed on 28 deaths from CO poisoning so far showed that this is generally possible. In almost all cases, the actual CO-Hb values could be estimated correctly by using the Monte Carlo simulations.
DOI：
10.1364/josaa.16.001066
发表时间：
1999-05
期刊：
Journal of the Optical Society of America. A, Optics, image science, and vision
影响因子：
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作者：
Raphael Aronson;Noel Corngold
通讯作者：
Raphael Aronson;Noel Corngold
影响因子：
6.5
作者：
ANDERSON, RR;PARRISH, JA
通讯作者：
PARRISH, JA