An "off-the-shelf" capillary microfluidic device that enables tuning of the droplet breakup regime at constant flow rates.

An "off-the-shelf" capillary microfluidic device that enables tuning of the droplet breakup regime at constant flow rates.
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DOI:
10.1039/c3lc50804h
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发表时间:
2013-12-07
期刊:
影响因子:
6.1
通讯作者:
Prud'homme RK
Prud'homme RK
中科院分区:
工程技术1区
文献类型:
--
作者:
Benson BR;Stone HA;Prud'homme RK

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玻璃毛细管微流控装置的制造在技术上具有挑战性,往往阻碍了设计的使用。我们描述了一种基于商用组件的新技术,用于组装流动聚焦毛细管装置,该装置可以在使用之间容易地拆卸和清洗。这种设计策略允许在乙醇冲洗后在同一装置中生成油包水和水包油乳液。该装置的模块化能够在液滴产生过程中调节两个内部毛细血管之间的尖端分离,从而能够调节界面的年龄。随时间变化的表面活性剂向界面的扩散改变了界面张力,从而提供了一种在通常改变流速的方法之外调节毛细管数的方法。这种设计能够调整破碎模式和液滴大小。
The fabrication of glass capillary microfluidic devices is technically challenging, often hampering use of the design. We describe a new technique, based on commercially available components, for assembling flow focusing capillary devices that can readily be taken apart and cleaned between uses. This design strategy allows for generation of both water-in-oil and oil-in-water emulsions in the same device after an ethanol rinse. The modularity of the device enables the adjustment of the tip separation between the two inner capillaries during droplet generation, which enables tuning of the age of the interface. Time-dependent surfactant diffusion to the interface changes the interfacial tension, thus providing an approach for adjusting the capillary number in addition to the usual method of changing flow rates. This design enables the tuning of the mode of breakup and the droplet size.
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发表时间: 2013-01-01
期刊: LAB ON A CHIP
影响因子: 6.1
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