Predictability of intraocular lens calculation and early refractive status: the Infant Aphakia Treatment Study.
Predictability of intraocular lens calculation and early refractive status: the Infant Aphakia Treatment Study.
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DOI：
10.1001/archophthalmol.2011.358
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发表时间：
2012-03
影响因子：
--
通讯作者：
Lambert, Scott R.
中科院分区：
文献类型：
--
作者：
VanderVeen, Deborah K.;Nizam, Azhar;Lynn, Michael J.;Bothun, Erick D.;McClatchey, Scott K.;Weakley, David R.;DuBois, Lindreth G.;Lambert, Scott R.
目的：报道婴儿无晶状体治疗研究中人工晶状体（IOL）度数计算的准确性和婴儿假晶状体眼的早期屈光状态。使用Holladay 1配方，随机选择接受初级人工晶状体植入术的眼睛，术后28至48天的婴儿屈光度为+8.0 (D)，≥49天至<7个月的婴儿屈光度为+6.0 D。术后1个月的屈光度转换为球面等效，计算预测误差（PE=计算-实际屈光度）和绝对PE。分析基线眼睛和手术特征以及a扫描质量，比较它们对PE的影响。56眼植入术，7眼因术后屈光不足（n=5）或屈光技术不正确（n=1）或生物统计学（n=1）而被排除。总体平均绝对PE为1.8±1.3 D，平均PE为+1.0±2.0 D， 41%的眼绝对PE <1 D， 41%的眼绝对PE >2 D。平均人工晶状体度数29.9 D（范围：11.5 D ~ 40.0 D）；≥30.0 D的人工晶状体术后远视较少，占88%。多因素分析显示，只有较短的轴长（<18mm）与较高的PE有显著关系。较短的眼轴长度与婴儿人工晶状体置放后较高的人工晶体渗透性相关。眼轴长度< 18mm或高倍率iol的远视发生率低于预期。高质量的a扫描是必不可少的；高PE是常见的，远视倾向比预期的少。
To report accuracy of intraocular lens (IOL) power calculations and early refractive status in pseudophakic eyes of infants in the Infant Aphakia Treatment Study. Eyes randomized to receive primary IOL implantation were targeted for a postoperative refraction of +8.0 diopters (D) for infants 28 to 48 days at surgery and +6.0 D for ≥49 days to <7 months at surgery using the Holladay 1 formula. Refraction one month after surgery was converted to spherical equivalent, and prediction error (PE=calculated − actual refraction) and absolute PE were calculated. Baseline eye and surgery characteristics and A-scan quality were analyzed to compare their effect on PE. Prediction error 56 eyes had primary IOL implantation, 7 were excluded for lack of postoperative refraction (n=5) or incorrect technique in refraction (n=1) or biometry (n=1). Overall mean absolute PE was 1.8 ± 1.3 D and mean PE was +1.0 ±2.0 D. Absolute PE was <1 D in 41% of eyes, but >2 D in 41% of eyes. Mean IOL power implanted was 29.9 D (range, 11.5 D–40.0 D); most eyes (88%) implanted with IOL ≥30.0 D had less postoperative hyperopia than planned. Multivariate analysis showed only short axial length (<18mm) was significant for higher PE. Short axial length correlates with higher PE after IOL placement in infants. Less hyperopia than anticipated occurs with axial length <18 mm or high power IOLs. Quality A-scans are essential; higher PE is common, with tendency for less hyperopia than expected.
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影响因子：
1.6
作者：
Ben-Zion, Itay;Neely, Daniel E.;Roberts, Gavin J.
通讯作者：
Roberts, Gavin J.
影响因子：
2.8
作者：
Holladay, JT
通讯作者：
Holladay, JT
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2.8
作者：
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作者：
Trivedi, Rupal H.;Wilson, M. Edward
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Wilson, M. Edward
影响因子：
--
作者：
Lambert, Scott R.;Buckley, Edward G.;Ward, Michael
通讯作者：
Ward, Michael