Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa
Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa
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神经性厌食症急性病患者和体重恢复患者的时间延迟贴现
DOI：
10.1017/s0033291714002311
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发表时间：
2015
影响因子：
6.9
通讯作者：
Stefan Ehrlich
中科院分区：
文献类型：
--
作者：
Franziska Ritschel;Joseph A. King;Daniel Geisler;L. Flohr;F. Neidel;Ilka Boehm;M. Seidel;Johannes Zwipp;S. Ripke;Michael N. Smolka;Veit Roessner;Stefan Ehrlich
背景。神经性厌食症（AN）患者的特点是体重很低，但为了长期目标（苗条的身材），他们很容易放弃眼前的奖励（食物），这可能表明他们的自我控制水平不寻常。这种日常临床观察可以在预期-贴现困境的框架下量化。方法。本研究采用横断面设计，比较了34例急性AN （acAN）患者、33例体重恢复型AN （recAN）患者和54例健康对照者的延迟奖赏能力。我们还使用了一项纵向研究来重新评估21例短期体重恢复后的acAN患者。一个验证的跨期选择任务和双曲线模型被用来估计时间折现率。结果。证实了所使用任务的有效性，延迟折扣的减少与年龄和低自我报告的冲动性有关。然而，在货币奖励的时间折扣的关键措施中，没有发现组间差异。结论。认知控制的增强，被认为是AN的一个关键特征，似乎并没有延长等待延迟金钱奖励的能力。我们的研究与之前唯一一项报告成人AN患者延迟折扣减少的研究之间的差异可能是由于急性患者的年龄范围和慢性程度不同，但体重恢复与贴现率的变化无关的事实表明，折扣行为不是AN的特征标记。未来使用障碍特异性刺激范式的研究可能有助于阐明延迟折扣在AN中的作用。
Background. Patients with anorexia nervosa (AN) are characterized by a very low body weight but readily give up immediate rewards (food) for long-term goals (slim figure), which might indicate an unusual level of self-control. This everyday clinical observation may be quantifiable in the framework of the anticipation-discounting dilemma. Method. Using a cross-sectional design, this study compared the capacity to delay reward in 34 patients suffering from acute AN (acAN), 33 weight-recovered AN patients (recAN) and 54 healthy controls. We also used a longitudinal study to reassess 21 acAN patients after short-term weight restoration. A validated intertemporal choice task and a hyperbolic model were used to estimate temporal discounting rates. Results. Confirming the validity of the task used, decreased delay discounting was associated with age and low self-reported impulsivity. However, no group differences in key measures of temporal discounting of monetary rewards were found. Conclusions. Increased cognitive control, which has been suggested as a key characteristic of AN, does not seem to extend the capacity to wait for delayed monetary rewards. Differences between our study and the only previous study reporting decreased delay discounting in adult AN patients may be explained by the different age range and chronicity of acute patients, but the fact that weight recovery was not associated with changes in discount rates suggests that discounting behavior is not a trait marker in AN. Future studies using paradigms with disorder-specific stimuli may help to clarify the role of delay discounting in AN.
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影响因子：
17.7
作者：
Wagner, Angela;Aizenstein, Howard;Kaye, Walter H.
通讯作者：
Kaye, Walter H.
影响因子：
2.7
作者：
Johnson, MW;Bickel, WK
通讯作者：
Bickel, WK
影响因子：
--
作者：
Patrick, K;Norman, GJ;Cella, J
通讯作者：
Cella, J
影响因子：
3.4
作者：
Kobiella, Andrea;Ripke, Stephan;Smolka, Michael N.
通讯作者：
Smolka, Michael N.
影响因子：
4.1
作者：
Kirby, KN;Petry, NM;Bickel, WK
通讯作者：
Bickel, WK