Cystic macular oedema on spectral-domain optical coherence tomography in choroideremia patients without cystic changes on fundus examination.

Cystic macular oedema on spectral-domain optical coherence tomography in choroideremia patients without cystic changes on fundus examination.
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DOI:
10.1038/eye.2010.157
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发表时间:
2011-01
期刊:
EYE
影响因子:
3.9
通讯作者:
Fishman, G. A.
Fishman, G. A.
中科院分区:
医学3区
文献类型:
--
作者:
Genead, M. A.;Fishman, G. A.

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利用光谱域光学相干断层扫描(SD-OCT)确定脉络膜血症患者囊性黄斑水肿(CME)的患病率。16例脉络膜血症患者参加了这项研究。所有患者都进行了全面的眼科检查。使用OPKO光谱域OCT/SLO仪器进行SD-OCT。研究患者的平均年龄为44.0±16.0岁(范围13-63岁)。在16例脉络膜血症患者中,10例患者(62.5%)在SD-OCT测试中至少在一只眼睛显示一定程度的CME, 8例患者(50%)在两只眼睛显示CME。由于其显著的普遍性,通过SD-OCT筛查脉络膜血症患者是否可能存在CME,并确定那些适合未来黄斑水肿治疗策略的患者似乎是谨慎的。
To determine the prevalence of cystic macular edema (CME) in patients with choroideremia by using spectral-domain optical coherence tomography (SD-OCT). Sixteen patients affected with choroideremia were enrolled in the study. All patients underwent a complete eye examination. SD-OCT was performed using an OPKO spectral-domain OCT/SLO instrument. The average age of the study patients was 44.0 ± 16.0 years (range, 13–63 years). Out of the 16 patients with choroideremia, 10 patients (62.5%) showed a degree of CME on SD-OCT testing in at least one eye, and 8 patients (50%) showed CME in both eyes. Because of its notable prevalence, it would seem prudent to screen choroideremia patients by SD-OCT for the possible presence of CME and to identify those amenable to future treatment strategies for their macular edema.
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