Neurocognitive and Fine Motor Deficits in Asymptomatic Adolescents during the Subacute Period after Concussion.

Neurocognitive and Fine Motor Deficits in Asymptomatic Adolescents during the Subacute Period after Concussion.
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脑震荡后亚急性期无症状青少年的神经认知和精细运动缺陷。

DOI:
10.1089/neu.2017.5314
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发表时间:
2018
影响因子:
4.2
通讯作者:
Mazzola,CatherineA
Mazzola,CatherineA
中科院分区:
医学2区
文献类型:
--
作者:
Servatius,RichardJ;Spiegler,KevinM;Handy,JustinD;Pang,KevinCH;Tsao,JackW;Mazzola,CatherineA

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青少年持续脑震荡的风险很高。关于神经认知测试在脑震荡后检测和跟踪功能障碍的敏感性存在相当大的争议。在脑震荡恢复的亚急性期比较两种神经认知测试组合,以确定对脑震荡的敏感性。通过脑震荡诊所招募了诊断为脑震荡的青少年(11-17岁)(8名男性,7名女性,受伤后9-69天),并与社区非脑震荡志愿者(11名男性,3名女性)进行比较。青少年在台式电脑上完成了在线版本的脑震荡后立即评估和认知测试(ImPACT),在手持设备上完成了防御自动神经行为评估(DANA),以及评估手动灵活性的凹槽钉板测试和运动速度。在脑震荡后症状量表上,脑震荡和非脑震荡青少年的自我报告症状没有差异。在ImPACT性能方面未观察到显著的组间差异。DANA评估的表现缺陷是明显的,反映了脑震荡患者简单反应时间和反应抑制参数的低通量评分。脑震荡的青少年也有较慢的槽钉板测试性能时,使用非优势的手。DANA测试组合和凹槽钉板测试似乎都有希望作为检测脑震荡后亚急性期持续认知和运动功能障碍的工具。
Adolescents are at high risk for sustaining concussions. There is considerable controversy regarding the sensitivity of neurocognitive tests to detect and track dysfunction in the aftermath of concussion. Two neurocognitive test batteries were compared during the subacute phase of recovery from concussion to determine sensitivity to concussion. Adolescents (ages 11–17 years) with a concussion diagnosis (eight males, seven females, 9–69 days after injury) were recruited through a concussion clinic and compared with community nonconcussed volunteers (11 males, three females). Adolescents completed the online version of the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) on a desktop computer and the Defense Automated Neurobehavioral Assessment (DANA) on a handheld device, as well as the Grooved Pegboard Test, which assessed manual dexterity and motor speed. There were no differences in self-reported symptoms on the Post-Concussion Symptom Scale comparing concussed and nonconcussed adolescents. No significant between-groups differences were observed in ImPACT performance. Performance deficits were apparent for the DANA assessment, reflecting lower throughput scores for simple reaction time and response inhibition parameters in those with concussion. Concussed adolescents also had slower Grooved Pegboard Test performance when using the nondominant hand. Both the DANA test battery and the Grooved Pegboard Test appear to have promise as tools to detect persistent cognitive and motor dysfunction in the subacute period after concussion.
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