The BIG Data Center: from deposition to integration to translation.

The BIG Data Center: from deposition to integration to translation.
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大数据中心:从沉积到集成再到转换。

DOI:
10.1093/nar/gkw1060
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
BIG Data Center Members
BIG Data Center Members
中科院分区:
生物学2区
文献类型:
--
作者:
BIG Data Center Members

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生物数据以前所未有的指数级速度生成,这对大数据的存储、集成和转换提出了相当大的挑战。BIG数据中心建立在中国科学院北京基因组研究所(BIG),提供一套数据库资源,包括(i)基因组序列档案,专门用于存档原始序列读数的数据库,(ii)基因表达星云,完全基于RNA-Seq数据的基因表达谱数据门户,(iii)基因组变异图谱,(iv)基因组仓库,一个集中的资源库,储存基因组规模的数据,特别关注经济上重要的动物和植物,(v)甲基化银行,一个全基因组单碱基分辨率甲基化组的综合数据库,以及(vi)科学维基,为社区注释开发的生物维基的中央访问点。BIG数据中心致力于通过大数据整合和增值策展来构建和维护生物数据库,开展基础研究以将大数据转化为大知识,并提供免费开放的各种数据资源,以支持学术界和工业界的全球研究活动。所有这些资源都是公开的,可以在http://bigd.big.ac.cn上找到。
Biological data are generated at unprecedentedly exponential rates, posing considerable challenges in big data deposition, integration and translation. The BIG Data Center, established at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences, provides a suite of database resources, including (i) Genome Sequence Archive, a data repository specialized for archiving raw sequence reads, (ii) Gene Expression Nebulas, a data portal of gene expression profiles based entirely on RNA-Seq data, (iii) Genome Variation Map, a comprehensive collection of genome variations for featured species, (iv) Genome Warehouse, a centralized resource housing genome-scale data with particular focus on economically important animals and plants, (v) Methylation Bank, an integrated database of whole-genome single-base resolution methylomes and (vi) Science Wikis, a central access point for biological wikis developed for community annotations. The BIG Data Center is dedicated to constructing and maintaining biological databases through big data integration and value-added curation, conducting basic research to translate big data into big knowledge and providing freely open access to a variety of data resources in support of worldwide research activities in both academia and industry. All of these resources are publicly available and can be found at http://bigd.big.ac.cn.
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