Unfolding the Mild to Moderate Short-Term Side Effects of Four COVID-19 Vaccines Used in Bahrain: A Cross-Sectional Study.
Unfolding the Mild to Moderate Short-Term Side Effects of Four COVID-19 Vaccines Used in Bahrain: A Cross-Sectional Study.
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DOI：
10.3390/vaccines9111369
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发表时间：
2021-11-22
期刊：
影响因子：
7.8
通讯作者：
Zahid MN
中科院分区：
文献类型：
--
作者：
Zahid MN
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引发了一场全球大流行(新冠肺炎)，造成了巨大的健康和经济损失。由于目前没有治疗方法，因此接种疫苗是控制这种疾病的唯一途径。巴林有四种疫苗(国药、辉瑞生物科技、Sputnik和阿斯利康)。该项目旨在研究这四种疫苗第一针和第二针最常见的副作用。数据是通过311名接种了这四种疫苗之一的两剂疫苗的人回答的在线问卷收集的。这项研究的结果显示，无论疫苗身份如何，参与者在第二剂疫苗中都会经历更多的副作用。在不同的副作用中，注射部位的疼痛主要发生在第一剂辉瑞疫苗(43%)之后，其次是阿斯利康疫苗(31%)。此外，参与者在第一次接种Sputnik疫苗后出现发烧(37%)，而头痛主要出现在第一次接种辉瑞疫苗后(32%)。值得注意的是，在所有四种疫苗的第一次接种后都观察到了疲劳，但在辉瑞公司组中报告的受访者比例最高(28%)。有趣的是，有一些副作用，如注射部位的疼痛，与发烧有关(r=0.909)。同样，头痛与发热(r=0.801)和注射部位疼痛(r=0.868)相关。总体而言，据观察，国药疫苗的接受者报告的副作用在所有四种疫苗中最轻。这项研究的关键发现是，第一剂和第二剂疫苗接种后的副作用是温和的和可预测的，没有发生住院事件；这一信息有助于减少对疫苗的担忧。
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) created a global pandemic (COVID-19) that has resulted in massive health and economic losses. The current unavailability of treatments leaves vaccination as the only way to control this disease. There are four vaccines (Sinopharm, Pfizer—BioNTech, Sputnik, and AstraZeneca) available in Bahrain. This project aimed to study the most common side effects resulting from the first and second doses of these four vaccines. Data were collected through an online questionnaire answered by 311 individuals who received both doses of one of these four vaccines. The results of this study revealed that regardless of the vaccine identity, participants experienced more side effects from the second dose. Among the different side effects, pain at the site of injection was primarily observed after the first dose of the Pfizer vaccine (43%), which was followed by the AstraZeneca vaccine (31%). Moreover, fever was observed in participants after the first dose of the Sputnik vaccine (37%), while headache was mainly observed after the first dose of the Pfizer vaccine (32%). It is important to note that fatigue was observed after the first dose of all four vaccines but was reported by the highest proportion of respondents in the Pfizer group (28%). Interestingly, there are some side effects, such as pain at the site of injection, that are correlated with fever (r = 0.909). Similarly, headache is correlated with fever (r = 0.801) and pain at the site of injection (r = 0.868). Overall, it was observed that recipients of the Sinopharm vaccine reported the mildest side effects among all four vaccines. The crucial finding of this study is that the first and second dosage post-vaccination side effects were modest and predictable with no occurrences of hospitalization; this information can assist in lessening vaccine apprehension.
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DOI：
10.1016/j.dsx.2021.102207
发表时间：
2021-09
期刊：
Diabetes & metabolic syndrome
影响因子：
--
作者：
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通讯作者：
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影响因子：
3.9
作者：
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影响因子：
3.7
作者：
Leite JA;Gresh L;Vicari A;Gabastou JM;Perez E;Aldighieri S;SARINET laboratories Network;Mendez-Rico J
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Mendez-Rico J
影响因子：
2.6
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Galindo R;Chow H;Rongkavilit C
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