A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications
A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications
复制标题
用于 NanoESI-MS 微流体应用的平面片上微笔尖接口
DOI:
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发表时间:
2004
期刊:
影响因子:
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通讯作者:
C. Rolando
中科院分区:
文献类型:
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作者:
S. Arscott;S. Gac;C. Druon;P. Tabourier;C. Rolando
We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization–mass spectrometry (ESI–MS) applications. The fabrication of the micro-nibs relies on micromachining techniques using the epoxy-based negative photoresist SU-8. A double exposure photolithographic process has been employed to form a nib in a membrane-like structure. The nibs contained a capillary slot measuring 20 µm at the tip end. The nib sources were successfully tested on an ion trap mass spectrometer using standard peptide samples at low concentrations, down to 1 µM. High voltage (HV) supply was achieved using platinum wire inserted in a liquid reservoir. A Taylor cone was clearly seen protruding from the nib tip and was determined by the dimensions of the capillary slot.
影响因子:
7.4
作者:
Licklider, L;Wang, XQ;Lee, TD
通讯作者:
Lee, TD
影响因子:
7.4
作者:
Xue, QF;Foret, F;Karger, BL
通讯作者:
Karger, BL
影响因子:
7.4
作者:
Tang, KQ;Lin, YH;Smith, RD
通讯作者:
Smith, RD