Quasilinear viscoelastic behavior of bovine extraocular muscle tissue.
Quasilinear viscoelastic behavior of bovine extraocular muscle tissue.
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DOI：
10.1167/iovs.08-3245
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发表时间：
2009-08
影响因子：
4.4
通讯作者：
Demer JL
中科院分区：
文献类型：
--
作者：
Yoo L;Kim H;Gupta V;Demer JL
迄今为止，还没有一个全面的眼外肌非线性粘弹性应力-应变行为的数学模型。本研究描述了，与准线性粘弹性（QLV）模型的使用，非线性，历史依赖的粘弹性性能和弹性应力-应变关系的EOMs。从当地屠宰场新鲜获得六个眼动眼外膜。纵向取向的试样取自不同区域的EOM和进行单轴拉伸，松弛，和循环载荷测试与温度和湿度控制下使用的自动测力传感器。12个样品以1.7%/s的应变速率经受单轴拉伸载荷直至失效。对16个样本进行了超过1500秒的松弛研究。进行循环加载以验证QLV模型的预测，其特征在于单轴拉伸加载和松弛数据。均匀和高度可重复的应力-应变行为，观察12个标本提取的各个区域的所有EOM。来自16个不同松弛试验的结果表明，对于30%的延伸，大多数应力松弛发生在前30至60秒期间。弹性和减少松弛函数拟合的数据，从QLV模型组装和循环加载数据进行比较。对于所有样本和条件，QLV模型的预测与观察到的峰值循环载荷应力值一致，在8%以内。QLV模型与松弛和循环载荷数据之间的密切一致性验证了EOM机械性能的模型量化，并将允许开发准确的眼球运动和斜视力学的整体模型。
Until now, there has been no comprehensive mathematical model of the nonlinear viscoelastic stress-strain behavior of extraocular muscles (EOMs). The present study describes, with the use of a quasilinear viscoelastic (QLV) model, the nonlinear, history-dependent viscoelastic properties and elastic stress-strain relationship of EOMs. Six oculorotary EOMs were obtained fresh from a local abattoir. Longitudinally oriented specimens were taken from different regions of the EOMs and subjected to uniaxial tensile, relaxation, and cyclic loading testing with the use of an automated load cell under temperature and humidity control. Twelve samples were subjected to uniaxial tensile loading with 1.7%/s strain rate until failure. Sixteen specimens were subjected to relaxation studies over 1500 seconds. Cyclic loading was performed to validate predictions of the QLV model characterized from uniaxial tensile loading and relaxation data. Uniform and highly repeatable stress-strain behavior was observed for 12 specimens extracted from various regions of all EOMs. Results from 16 different relaxation trials illustrated that most stress relaxation occurred during the first 30 to 60 seconds for 30% extension. Elastic and reduced relaxation functions were fit to the data, from which a QLV model was assembled and compared with cyclic loading data. Predictions of the QLV model agreed with observed peak cyclic loading stress values to within 8% for all specimens and conditions. Close agreement between the QLV model and the relaxation and cyclic loading data validates model quantification of EOM mechanical properties and will permit the development of accurate overall models of mechanics of ocular motility and strabismus.
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影响因子：
2
作者：
Chaudhry, HR;Bukiet, B;Ritter, AB
通讯作者：
Ritter, AB
影响因子：
2.4
作者：
EGAN, JM
通讯作者：
EGAN, JM
影响因子：
2.4
作者：
Farshad, M;Barbezat, M;Niederer, P
通讯作者：
Niederer, P
DOI：
10.1115/1.2795963
发表时间：
1996-05-01
影响因子：
1.7
作者：
Johnson, GA;Livesay, GA;Rajagopal, KR
通讯作者：
Rajagopal, KR
DOI：
10.1115/1.2895527
发表时间：
1993-11-01
影响因子：
1.7
作者：
LAI, WM;MOW, VC;ZHU, WB
通讯作者：
ZHU, WB