What Causes Anterograde Amnesia?
What Causes Anterograde Amnesia?
复制标题
顺行性遗忘症的原因是什么？
DOI：
10.1159/000512408
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发表时间：
2021-04
影响因子：
2.4
通讯作者：
Xiuli Shang
中科院分区：
文献类型：
--
作者：
Jiwei Jiang;Xiaoting Wang;Yutong Chen;Xiuli Shang
A 49-year-old woman with poorly controlled hypertension was admitted to our hospital for sudden memory deficit. Her daughter noticed that she repeatedly asked about the time for lunch on the day before admission and her inability to recall storylines on television programs. However, the patient recognized her daughter and other family members. She did not experience fatigue, fever, or diarrhea before the onset of amnesia. Her memory impairment was persistent. Headaches, convulsions, or limb movement disorders were absent. She had no history of smoking, drinking, trauma, drug abuse, or exposure to toxins. The findings of the neurological examination were unremarkable, except for the reduction in memory and calculation abilities, which manifested as the inability to recall incidents that occurred minutes ago, along with reiterations of the same questions. Her Mini-Mental State Examination score was 21, with deficits in the immediate memory (0/3), recall (0/3), and calculation (2/5) categories. The result of the Montreal Objective Cognitive Assessment was normal, with the exception of recall and calculation.The patient’s blood pressure at admission was 170/105 mm Hg. Serum total cholesterol and low-density lipoprotein levels were elevated, while other laboratory tests for blood cell counts, glucose, ion concentration, human immunodeficiency virus and syphilis antibodies, vitamin B1, vitamin B12, and folate, and liver, renal, and thyroid functions were normal. Cerebrospinal fluid assessment yielded normal results. The inflammatory, infectious, and immune biomarkers in cerebrospinal fluid were unremarkable. Brain magnetic resonance imaging (MRI) demonstrated symmetrical restricted diffusion signals in the bilateral fornicolumns on axial diffusion-weighted imaging, with corresponding hypointensities on the apparent diffusion coefficient map (shown in Fig. 1), without abnormal signals in the established memory-related regions or other regions of the fornix (shown in Fig. 2). The findings of Holter electrocardiography, transthoracic echocardiography, and magnetic resonance angiography were normal. Treatment consisted of aspirin (100 mg/day), atorvastatin (20 mg/night), and butylphthalide administration to improve cerebral circulation and extended-release nifedipine tablets (30 mg/day) to control blood pressure, which resulted in the amelioration of the neurological symptoms.
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影响因子：
8.3
作者：
Michel, Patrik;Beaud, Valerie;Eskioglou, Elissavet
通讯作者：
Eskioglou, Elissavet
影响因子：
16.6
作者：
Ferguson, Michael A.;Lim, Chun;Fox, Michael D.
通讯作者：
Fox, Michael D.
影响因子：
9.9
作者：
G. Pergola
通讯作者：
G. Pergola
影响因子：
5.1
作者：
A. Salvalaggio;A. Cagnin;L. Nardetto;R. Manara;C. Briani
通讯作者：
A. Salvalaggio;A. Cagnin;L. Nardetto;R. Manara;C. Briani
影响因子：
2.7
作者：
Fournier, Danielle, I;Eddy, Meghan C.;Bucci, David J.
通讯作者：
Bucci, David J.