Concentration and state dependent reductions in corn oil intakes after glossopharyngeal nerve transections in rats.

Concentration and state dependent reductions in corn oil intakes after glossopharyngeal nerve transections in rats.
复制标题

脑咽咽神经过晶的玉米油摄入量的浓度和状态依赖性降低。

DOI:
10.1016/j.physbeh.2014.02.018
复制
发表时间:
2014-04-10
影响因子:
2.9
通讯作者:
Norgren R
Norgren R
中科院分区:
医学3区
文献类型:
--
作者:
Foo H;Norgren R

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先前的研究表明,舌咽神经(GL)在检测膳食脂肪中的作用。本实验研究了双侧舌咽神经横断(GLx)对非剥夺、食物剥夺和水剥夺大鼠摄入低(4.8%)、中等(16%)和全脂(100%)玉米油的影响。大鼠可以在味觉计中获得油、0.3 M蔗糖和水,味觉计在短暂的获得试验期间测量舔次数和第一次舔的潜伏期。行为测量分别被用作消费量和摄入动机的指数。基线摄入量稳定后,大鼠接受GLx或假横断(Sham),然后重新测试。比较术前和术后反应,以确定GLx对摄入的影响和摄入的动机。在非剥夺大鼠中,GLx减少了4.8%和16%油的摄入量,并降低了摄入这些油的动机。在食物剥夺的大鼠中,GLx阻止了4.8%和16%油的摄入量增加以及摄入这些油的动机增加。在缺水的大鼠中,GLx减少了100%油的摄入量,并普遍降低了消耗低脂、中脂和全脂乳剂的动机。这些结果表明,GL是部分参与玉米油的摄入量,并建议油浓度与稳态的相互作用。
Previous studies indicate a role for the glossopharyngeal nerve (GL) in the detection of dietary fats. The present experiments examined the effects of bilateral glossopharyngeal nerve transections (GLx) on the intake of low (4.8%), moderate (16%), and full-fat (100%) corn oil in non-deprived, food-deprived, and water-deprived rats. The rats had access to oils, 0.3 M sucrose, and water in a gustometer that measured number of licks and latency to the first lick during brief access trials. The behavioral measures were used as indices of the amount consumed and the motivation to ingest, respectively. After baseline intakes had stabilized, the rats received GLx or sham transections (Sham), and were then re-tested. Pre and post-surgery responses were compared to determine the impact of GLx on intake and the motivation to ingest. In non-deprived rats, GLx reduced the intake of 4.8% and 16% oils and decreased the motivation to ingest these oils. In food-deprived rats, GLx prevented increases in the ingestion of 4.8% and 16% oils and in the motivation to ingest these oils. In water-deprived rats, GLx reduced the intake of 100% oil and produced a general decrease in the motivation to consume low, moderate, and full-fat emulsions. These results indicate that GL is partially involved in corn oil intake and suggest an interactive effect of oil concentration with homeostatic state.
DOI: 10.1016/s0031-9384(03)00201-4
发表时间: 2003-09-01
影响因子: 2.9
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发表时间: 2003-08-01
影响因子: 2.8
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