An integrated encyclopedia of DNA elements in the human genome.
An integrated encyclopedia of DNA elements in the human genome.
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DOI：
10.1038/nature11247
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发表时间：
2012-09-06
期刊：
影响因子：
64.8
通讯作者：
Birney, Ewan
中科院分区：
文献类型：
--
作者：
Dunham, Ian;Kundaje, Anshul;Aldred, Shelley F.;Collins, Patrick J.;Davis, CarrieA.;Doyle, Francis;Epstein, Charles B.;Frietze, Seth;Harrow, Jennifer;Kaul, Rajinder;Khatun, Jainab;Lajoie, Bryan R.;Landt, Stephen G.;Lee, Bum-Kyu;Pauli, Florencia;Rosenbloom, Kate R.;Sabo, Peter;Safi, Alexias;Sanyal, Amartya;Shoresh, Noam;Simon, Jeremy M.;Song, Lingyun;Trinklein, Nathan D.;Altshuler, Robert C.;Birney, Ewan;Brown, James B.;Cheng, Chao;Djebali, Sarah;Dong, Xianjun;Dunham, Ian;Ernst, Jason;Furey, Terrence S.;Gerstein, Mark;Giardine, Belinda;Greven, Melissa;Hardison, Ross C.;Harris, Robert S.;Herrero, Javier;Hoffman, Michael M.;Iyer, Sowmya;Kellis, Manolis;Khatun, Jainab;Kheradpour, Pouya;Kundaje, Anshul;Lassmann, Timo;Li, Qunhua;Lin, Xinying;Marinov, Georgi K.;Merkel, Angelika;Mortazavi, Ali;Parker, Stephen C. J.;Reddy, Timothy E.;Rozowsky, Joel;Schlesinger, Felix;Thurman, Robert E.;Wang, Jie;Ward, Lucas D.;Whitfield, Troy W.;Wilder, Steven P.;Wu, Weisheng;Xi, Hualin S.;Yip, Kevin Y.;Zhuang, Jiali;Bernstein, Bradley E.;Birney, Ewan;Dunham, Ian;Green, Eric D.;Gunter, Chris;Snyder, Michael;Pazin, Michael J.;Lowdon, Rebecca F.;Dillon, Laura A. L.;Adams, Leslie B.;Kelly, Caroline J.;Zhang, Julia;Wexler, Judith R.;Green, Eric D.;Good, Peter J.;Feingold, Elise A.;Bernstein, Bradley E.;Birney, Ewan;Crawford, Gregory E.;Dekker, Job;Elnitski, Laura;Farnham, Peggy J.;Gerstein, Mark;Giddings, Morgan C.;Gingeras, Thomas R.;Green, Eric D.;Guigo, Roderic;Hardison, Ross C.;Hubbard, Timothy J.;Kellis, Manolis;Kent, W. James;Lieb, Jason D.;Margulies, Elliott H.;Myers, Richard M.;Snyder, Michael;Stamatoyannopoulos, John A.;Tenenbaum, Scott A.;Weng, Zhiping;White, Kevin P.;Wold, Barbara;Khatun, Jainab;Yu, Yanbao;Wrobel, John;Risk, Brian A.;Gunawardena, Harsha P.;Kuiper, Heather C.;Maier, Christopher W.;Xie, Ling;Chen, Xian;Giddings, Morgan C.;Bernstein, Bradley E.;Epstein, Charles B.;Shoresh, Noam;Ernst, Jason;Kheradpour, Pouya;Mikkelsen, Tarjei S.;Gillespie, Shawn;Goren, Alon;Ram, Oren;Zhang, Xiaolan;Wang, Li;Issner, Robbyn;Coyne, Michael J.;Durham, Timothy;Ku, Manching;Truong, Thanh;Ward, Lucas D.;Altshuler, Robert C.;Eaton, Matthew L.;Kellis, Manolis;Djebali, Sarah;Davis, Carrie A.;Merkel, Angelika;Dobin, Alex;Lassmann, Timo;Mortazavi, Ali;Tanzer, Andrea;Lagarde, Julien;Lin, Wei;Schlesinger, Felix;Xue, Chenghai;Marinov, Georgi K.;Khatun, Jainab;Williams, Brian A.;Zaleski, Chris;Rozowsky, Joel;Roeder, Maik;Kokocinski, Felix;Abdelhamid, Rehab F.;Alioto, Tyler;Antoshechkin, Igor;Baer, Michael T.;Batut, Philippe;Bell, Ian;Bell, Kimberly;Chakrabortty, Sudipto;Chen, Xian;Chrast, Jacqueline;Curado, Joao;Derrien, Thomas;Drenkow, Jorg;Dumais, Erica;Dumais, Jackie;Duttagupta, Radha;Fastuca, Megan;Fejes-Toth, Kata;Ferreira, Pedro;Foissac, Sylvain;Fullwood, Melissa J.;Gao, Hui;Gonzalez, David;Gordon, Assaf;Gunawardena, Harsha P.;Howald, Cedric;Jha, Sonali;Johnson, Rory;Kapranov, Philipp;King, Brandon;Kingswood, Colin;Li, Guoliang;Luo, Oscar J.;Park, Eddie;Preall, Jonathan B.;Presaud, Kimberly;Ribeca, Paolo;Risk, Brian A.;Robyr, Daniel;Ruan, Xiaoan;Sammeth, Michael;Sandhu, Kuljeet Singh;Schaeffer, Lorain;See, Lei-Hoon;Shahab, Atif;Skancke, Jorgen;Suzuki, Ana Maria;Takahashi, Hazuki;Tilgner, Hagen;Trout, Diane;Walters, Nathalie;Wang, Huaien;Wrobel, John;Yu, Yanbao;Hayashizaki, Yoshihide;Harrow, Jennifer;Gerstein, Mark;Hubbard, Timothy J.;Reymond, Alexandre;Antonarakis, Stylianos E.;Hannon, Gregory J.;Giddings, Morgan C.;Ruan, Yijun;Wold, Barbara;Carninci, Piero;Guigo, Roderic;Gingeras, Thomas R.;Rosenbloom, Kate R.;Sloan, Cricket A.;Learned, Katrina;Malladi, Venkat S.;Wong, Matthew C.;Barber, Galtp.;Cline, Melissa S.;Dreszer, Timothy R.;Heitner, Steven G.;Karolchik, Donna;Kent, W. James;Kirkup, Vanessa M.;Meyer, Laurence R.;Long, Jeffrey C.;Maddren, Morgan;Raney, Brian J.;Furey, Terrence S.;Song, Lingyun;Grasfeder, Linda L.;Giresi, Paul G.;Lee, Bum-Kyu;Battenhouse, Anna;Sheffield, Nathan C.;Simon, Jeremy M.;Showers, Kimberly A.;Safi, Alexias;London, Darin;Bhinge, Akshay A.;Shestak, Christopher;Schaner, Matthew R.;Kim, Seul Ki;Zhang, Zhuzhu Z.;Mieczkowski, Piotr A.;Mieczkowska, Joanna O.;Liu, Zheng;McDaniell, Ryan M.;Ni, Yunyun;Rashid, Naim U.;Kim, Min Jae;Adar, Sheera;Zhang, Zhancheng;Wang, Tianyuan;Winter, Deborah;Keefe, Damian;Birney, Ewan;Iyer, Vishwanath R.;Lieb, Jason D.;Crawford, Gregory E.;Li, Guoliang;Sandhu, Kuljeet Singh;Zheng, Meizhen;Wang, Ping;Luo, Oscar J.;Shahab, Atif;Fullwood, Melissa J.;Ruan, Xiaoan;Ruan, Yijun;Myers, Richard M.;Pauli, Florencia;Williams, Brian A.;Gertz, Jason;Marinov, Georgi K.;Reddy, Timothy E.;Vielmetter, Jost;Partridge, E. Christopher;Trout, Diane;Varley, Katherine E.;Gasper, Clarke;Bansal, Anita;Pepke, Shirley;Jain, Preti;Amrhein, Henry;Bowling, Kevin M.;Anaya, Michael;Cross, Marie K.;King, Brandon;Muratet, Michael A.;Antoshechkin, Igor;Newberry, Kimberly M.;Mccue, Kenneth;Nesmith, Amy S.;Fisher-Aylor, Katherine I.;Pusey, Barbara;DeSalvo, Gilberto;Parker, Stephanie L.;Balasubramanian, Sreeram;Davis, Nicholas S.;Meadows, Sarah K.;Eggleston, Tracy;Gunter, Chris;Newberry, J. Scott;Levy, Shawn E.;Absher, Devin M.;Mortazavi, Ali;Wong, Wing H.;Wold, Barbara;Blow, Matthew J.;Visel, Axel;Pennachio, Len A.;Elnitski, Laura;Margulies, Elliott H.;Parker, Stephen C. J.;Petrykowska, Hanna M.;Abyzov, Alexej;Aken, Bronwen;Barrell, Daniel;Barson, Gemma;Berry, Andrew;Bignell, Alexandra;Boychenko, Veronika;Bussotti, Giovanni;Chrast, Jacqueline;Davidson, Claire;Derrien, Thomas;Despacio-Reyes, Gloria;Diekhans, Mark;Ezkurdia, Iakes;Frankish, Adam;Gilbert, James;Gonzalez, Jose Manuel;Griffiths, Ed;Harte, Rachel;Hendrix, David A.;Howald, Cedric;Hunt, Toby;Jungreis, Irwin;Kay, Mike;Khurana, Ekta;Kokocinski, Felix;Leng, Jing;Lin, Michael F.;Loveland, Jane;Lu, Zhi;Manthravadi, Deepa;Mariotti, Marco;Mudge, Jonathan;Mukherjee, Gaurab;Notredame, Cedric;Pei, Baikang;Rodriguez, Jose Manuel;Saunders, Gary;Sboner, Andrea;Searle, Stephen;Sisu, Cristina;Snow, Catherine;Steward, Charlie;Tanzer, Andrea;Tapanari, Electra;Tress, Michael L.;van Baren, Marijke J.;Walters, Nathalie;Washietl, Stefan;Wilming, Laurens;Zadissa, Amonida;Zhang, Zhengdong;Brent, Michael;Haussler, David;Kellis, Manolis;Valencia, Alfonso;Gerstein, Mark;Reymond, Alexandre;Guigo, Roderic;Harrow, Jennifer;Hubbard, Timothy J.;Landt, Stephen G.;Frietze, Seth;Abyzov, Alexej;Addleman, Nick;Alexander, Roger P.;Auerbach, Raymond K.;Balasubramanian, Suganthi;Bettinger, Keith;Bhardwaj, Nitin;Boyle, Alan P.;Cao, Alina R.;Cayting, Philip;Charos, Alexandra;Cheng, Yong;Cheng, Chao;Eastman, Catharine;Euskirchen, Ghia;Fleming, Joseph D.;Grubert, Fabian;Habegger, Lukas;Hariharan, Manoj;Harmanci, Arif;Iyengar, Sushma;Jin, Victor X.;Karczewski, Konrad J.;Kasowski, Maya;Lacroute, Phil;Lam, Hugo;Lamarre-Vincent, Nathan;Leng, Jing;Lian, Jin;Lindahl-Allen, Marianne;Min, Renqiang;Miotto, Benoit;Monahan, Hannah;Moqtaderi, Zarmik;Mu, Xinmeng J.;O'Geen, Henriette;Ouyang, Zhengqing;Patacsil, Dorrelyn;Pei, Baikang;Raha, Debasish;Ramirez, Lucia;Reed, Brian;Rozowsky, Joel;Sboner, Andrea;Shi, Minyi;Sisu, Cristina;Slifer, Teri;Witt, Heather;Wu, Linfeng;Xu, Xiaoqin;Yan, Koon-Kiu;Yang, Xinqiong;Yip, Kevin Y.;Zhang, Zhengdong;Struhl, Kevin;Weissman, Sherman M.;Gerstein, Mark;Farnham, Peggy J.;Snyder, Michael;Tenenbaum, Scott A.;Penalva, Luiz O.;Doyle, Francis;Karmakar, Subhradip;Landt, Stephen G.;Bhanvadia, Raj R.;Choudhury, Alina;Domanus, Marc;Ma, Lijia;Moran, Jennifer;Patacsil, Dorrelyn;Slifer, Teri;Victorsen, Alec;Yang, Xinqiong;Snyder, Michael;White, Kevin P.;Auer, Thomas;Centanin, Lazaro;Eichenlaub, Michael;Gruhl, Franziska;Heermann, Stephan;Hoeckendorf, Burkhard;Inoue, Daigo;Kellner, Tanja;Kirchmaier, Stephan;Mueller, Claudia;Reinhardt, Robert;Schertel, Lea;Schneider, Stephanie;Sinn, Rebecca;Wittbrodt, Beate;Wittbrodt, Jochen;Weng, Zhiping;Whitfield, Troy W.;Wang, Jie;Collins, Patrick J.;Aldred, Shelley F.;Trinklein, Nathan D.;Partridge, E. Christopher;Myers, Richard M.;Dekker, Job;Jain, Gaurav;Lajoie, Bryan R.;Sanyal, Amartya;Balasundaram, Gayathri;Bates, Daniel L.;Byron, Rachel;Canfield, Theresa K.;Diegel, Morgan J.;Dunn, Douglas;Ebersol, Abigail K.;Frum, Tristan;Garg, Kavita;Gist, Erica;Hansen, R. Scott;Boatman, Lisa;Haugen, Eric;Humbert, Richard;Jain, Gaurav;Johnson, Audra K.;Johnson, Ericka M.;Kutyavin, Tattyana V.;Lajoie, Bryan R.;Lee, Kristen;Lotakis, Dimitra;Maurano, Matthew T.;Neph, Shane J.;Neri, Fiedencio V.;Nguyen, Eric D.;Qu, Hongzhu;Reynolds, Alex P.;Roach, Vaughn;Rynes, Eric;Sabo, Peter;Sanchez, Minerva E.;Sandstrom, Richard S.;Sanyal, Amartya;Shafer, Anthony O.;Stergachis, Andrew B.;Thomas, Sean;Thurman, Robert E.;Vernot, Benjamin;Vierstra, Jeff;Vong, Shinny;Wang, Hao;Weaver, Molly A.;Yan, Yongqi;Zhang, Miaohua;Akey, Joshua M.;Bender, Michael;Dorschner, Michael O.;Groudine, Mark;MacCoss, Michael J.;Navas, Patrick;Stamatoyannopoulos, George;Kaul, Rajinder;Dekker, Job;Stamatoyannopoulos, John A.;Dunham, Ian;Beal, Kathryn;Brazma, Alvis;Flicek, Paul;Herrero, Javier;Johnson, Nathan;Keefe, Damian;Lukk, Margus;Luscombe, Nicholas M.;Sobral, Daniel;Vaquerizas, Juan M.;Wilder, Steven P.;Batzoglou, Serafim;Sidow, Arend;Hussami, Nadine;Kyriazopoulou-Panagiotopoulou, Sofia;Libbrecht, Max W.;Schaub, Marc A.;Kundaje, Anshul;Hardison, Ross C.;Miller, Webb;Giardine, Belinda;Harris, Robert S.;Wu, Weisheng;Bickel, Peter J.;Banfai, Balazs;Boley, Nathan P.;Brown, James B.;Huang, Haiyan;Li, Qunhua;Li, Jingyi Jessica;Noble, William Stafford;Bilmes, Jeffrey A.;Buske, Orion J.;Hoffman, Michael M.;Sahu, Avinash D.;Kharchenko, Peter V.;Park, Peter J.;Baker, Dannon;Taylor, James;Weng, Zhiping;Iyer, Sowmya;Dong, Xianjun;Greven, Melissa;Lin, Xinying;Wang, Jie;Xi, Hualin S.;Zhuang, Jiali;Gerstein, Mark;Alexander, Roger P.;Balasubramanian, Suganthi;Cheng, Chao;Harmanci, Arif;Lochovsky, Lucas;Min, Renqiang;Mu, Xinmeng J.;Rozowsky, Joel;Yan, Koon-Kiu;Yip, Kevin Y.;Birney, Ewan
人类基因组编码了生命的蓝图，但其近30亿个碱基中的绝大多数的功能是未知的。DNA元素百科全书（ENCODE）计划已经系统地绘制了转录、转录因子关联、染色质结构和组蛋白修饰的区域。这些数据使我们能够为80%的基因组分配生化功能，特别是在研究充分的蛋白质编码区之外。许多已发现的候选调控元件彼此之间以及与表达的基因之间存在物理联系，为基因调控机制提供了新的见解。新鉴定的元件还显示出与人类疾病相关的序列变异的统计对应性，从而可以指导对这种变异的解释。总的来说，该项目为我们的基因和基因组的组织和调控提供了新的见解，并为生物医学研究提供了广泛的功能注释资源。
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure, and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied protein-coding regions. Many discovered candidate regulatory elements are physically associated with one another and with expressed genes, providing new insights into the mechanisms of gene regulation. The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide interpretation of this variation. Overall the project provides new insights into the organization and regulation of our genes and genome, and an expansive resource of functional annotations for biomedical research.
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影响因子：
46.9
作者：
Ball, Madeleine P.;Li, Jin Billy;Gao, Yuan;Lee, Je-Hyuk;LeProust, Emily M.;Park, In-Hyun;Xie, Bin;Daley, George Q.;Church, George M.
通讯作者：
Church, George M.
影响因子：
7
作者：
Dostie, Josee;Richmond, Todd A.;Dekker, Job
通讯作者：
Dekker, Job
影响因子：
7
作者：
Boyle, Alan P.;Song, Lingyun;Furey, Terrence S.
通讯作者：
Furey, Terrence S.
DOI：
10.1101/sqb.2003.68.245
发表时间：
2003-01-01
期刊：
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
影响因子：
--
作者：
Chiaromonte, F;Weber, RJ;Haussler, D
通讯作者：
Haussler, D
影响因子：
64.8
作者：
Altshuler, David;Durbin, Richard M.;Abecasis, Goncalo R.;Bentley, David R.;Chakravarti, Aravinda;Clark, Andrew G.;Collins, Francis S.;De la Vega, Francisco M.;Donnelly, Peter;Egholm, Michael;Flicek, Paul;Gabriel, Stacey B.;Gibbs, Richard A.;Knoppers, Bartha M.;Lander, Eric S.;Lehrach, Hans;Mardis, Elaine R.;McVean, Gil A.;Nickerson, DebbieA.;Peltonen, Leena;Schafer, Alan J.;Sherry, Stephen T.;Wang, Jun;Wilson, Richard K.;Gibbs, Richard A.;Deiros, David;Metzker, Mike;Muzny, Donna;Reid, Jeff;Wheeler, David;Wang, Jun;Li, Jingxiang;Jian, Min;Li, Guoqing;Li, Ruiqiang;Liang, Huiqing;Tian, Geng;Wang, Bo;Wang, Jian;Wang, Wei;Yang, Huanming;Zhang, Xiuqing;Zheng, Huisong;Lander, Eric S.;Altshuler, David L.;Ambrogio, Lauren;Bloom, Toby;Cibulskis, Kristian;Fennell, Tim J.;Gabriel, Stacey B.;Jaffe, David B.;Shefler, Erica;Sougnez, Carrie L.;Bentley, David R.;Gormley, Niall;Humphray, Sean;Kingsbury, Zoya;Koko-Gonzales, Paula;Stone, Jennifer;McKernan, Kevin J.;Costa, Gina L.;Ichikawa, Jeffry K.;Lee, Clarence C.;Sudbrak, Ralf;Lehrach, Hans;Borodina, Tatiana A.;Dahl, Andreas;Davydov, Alexey N.;Marquardt, Peter;Mertes, Florian;Nietfeld, Wilfiried;Rosenstiel, Philip;Schreiber, Stefan;Soldatov, Aleksey V.;Timmermann, Bernd;Tolzmann, Marius;Egholm, Michael;Affourtit, Jason;Ashworth, Dana;Attiya, Said;Bachorski, Melissa;Buglione, Eli;Burke, Adam;Caprio, Amanda;Celone, Christopher;Clark, Shauna;Conners, David;Desany, Brian;Gu, Lisa;Guccione, Lorri;Kao, Kalvin;Kebbel, Andrew;Knowlton, Jennifer;Labrecque, Matthew;McDade, Louise;Mealmaker, Craig;Minderman, Melissa;Nawrocki, Anne;Niazi, Faheem;Pareja, Kristen;Ramenani, Ravi;Riches, David;Song, Wanmin;Turcotte, Cynthia;Wang, Shally;Mardis, Elaine R.;Dooling, David;Fulton, Lucinda;Fulton, Robert;Weinstock, George;Durbin, Richard M.;Burton, John;Carter, David M.;Churcher, Carol;Coffey, Alison;Cox, Anthony;Palotie, Aarno;Quail, Michael;Skelly, Tom;Stalker, James;Swerdlow, Harold P.;Turner, Daniel;De Witte, Anniek;Giles, Shane;Gibbs, Richard A.;Wheeler, David;Bainbridge, Matthew;Challis, Danny;Sabo, Aniko;Yu, Fuli;Yu, Jin;Wang, Jun;Fang, Xiaodong;Guo, Xiaosen;Li, Ruiqiang;Li, Yingrui;Luo, Ruibang;Tai, Shuaishuai;Wu, Honglong;Zheng, Hancheng;Zheng, Xiaole;Zhou, Yan;Yang, Huanming;Marth, Gabor T.;Garrison, Erik P.;Huang, Weichun;Indap, Amit;Kural, Deniz;Lee, Wan-Ping;Leong, Wen Fung;Huang, Weichun;Indap, Amit;Kural, Deniz;Lee, Wan-Ping;Leong, Wen Fung;Quinlan, Aaron R.;Stewart, Chip;Stromberg, Michael P.;Ward, Alistair N.;Wu, Jiantao;Lee, Charles;Mills, Ryan E.;Shi, Xinghua;Daly, Mark J.;DePristo, Mark A.;Altshuler, David L.;Ball, Aaron D.;Banks, Eric;Bloom, Toby;Browning, Brian L.;Cibulskis, Kristian;Fennell, Tim J.;Garimella, Kiran V.;Grossman, Sharon R.;Handsaker, Robert E.;Hanna, Matt;Hartl, Chris;Jaffe, David B.;Kernytsky, Andrew M.;Korn, Joshua M.;Li, Heng;Maguire, Jared R.;McCarroll, Steven A.;McKenna, Aaron;Nemesh, James C.;Philippakis, Anthony A.;Poplin, Ryan E.;Price, Alkes;Rivas, Manuel A.;Sabeti, Pardis C.;Schaffner, Stephen F.;Shefler, Erica;Shlyakhter, Ilya A.;Cooper, David N.;Ball, Edward V.;Mort, Matthew;Phillips, Andrew D.;Stenson, Peter D.;Sebat, Jonathan;Makarov, Vladimir;Ye, Kenny;Yoon, Seungtai C.;Bustamante, Carlos D.;Clark, Andrew G.;Boyko, Adam;Degenhardt, Jeremiah;Gravel, Simon;Gutenkunst, Ryan N.;Kaganovich, Mark;Keinan, Alon;Lacroute, Phil;Ma, Xia;Reynolds, Andy;Clarke, Laura;Flicek, Paul;Cunningham, Fiona;Herrero, Javier;Keenen, Stephen;Kulesha, Eugene;Leinonen, Rasko;McLaren, WilliamM.;Radhakrishnan, Rajesh;Smith, Richard E.;Zalunin, Vadim;Zheng-Bradley, Xiangqun;Korbel, Jan O.;Stuetz, Adrian M.;Humphray, Sean;Bauer, Markus;Cheetham, R. Keira;Cox, Tony;Eberle, Michael;James, Terena;Kahn, Scott;Murray, Lisa;Ye, Kai;De La Vega, Francisco M.;Fu, Yutao;Hyland, Fiona C. L.;Manning, Jonathan M.;McLaughlin, Stephen F.;Peckham, Heather E.;Sakarya, Onur;Sun, Yongming A.;Tsung, Eric F.;Batzer, Mark A.;Konkel, Miriam K.;Walker, Jerilyn A.;Sudbrak, Ralf;Albrecht, Marcus W.;Amstislavskiy, Vyacheslav S.;Herwig, Ralf;Parkhomchuk, Dimitri V.;Sherry, Stephen T.;Agarwala, Richa;Khouri, Hodam.;Morgulis, Aleksandr O.;Paschall, Justin E.;Phan, Lon D.;Rotmistrovsky, Kirill E.;Sanders, Robert D.;Shumway, Martin F.;Xiao, Chunlin;McVean, Gil A.;Auton, Adam;Iqbal, Zamin;Lunter, Gerton;Marchini, Jonathan L.;Moutsianas, Loukas;Myers, Simon;Tumian, Afidalina;Desany, Brian;Knight, James;Winer, Roger;Craig, David W.;Beckstrom-Sternberg, Steve M.;Christoforides, Alexis;Kurdoglu, Ahmet A.;Pearson, Johnv.;Sinari, Shripad A.;Tembe, Waibhav D.;Haussler, David;Hinrichs, Angie S.;Katzman, Sol J.;Kern, Andrew;Kuhn, Robert M.;Przeworski, Molly;Hernandez, Ryan D.;Howie, Bryan;Kelley, Joanna L.;Melton, S. Cord;Abecasis, Goncalo R.;Li, Yun;Anderson, Paul;Blackwell, Tom;Chen, Wei;Cookson, William O.;Ding, Jun;Kang, Hyun Min;Lathrop, Mark;Liang, Liming;Moffatt, Miriam F.;Scheet, Paul;Sidore, Carlo;Snyder, Matthew;Zhan, Xiaowei;Zoellner, Sebastian;Awadalla, Philip;Casals, Ferran;Idaghdour, Youssef;Keebler, John;Stone, Eric A.;Zilversmit, Martine;Jorde, Lynn;Xing, Jinchuan;Eichler, Evan E.;Aksay, Gozde;Alkan, Can;Hajirasouliha, Iman;Hormozdiari, Fereydoun;Kidd, Jeffrey M.;Sahinalp, S. Cenk;Sudmant, Peter H.;Mardis, Elaine R.;Chen, Ken;Chinwalla, Asif;Ding, Li;Koboldt, Daniel C.;McLellan, Mike D.;Dooling, David;Weinstock, George;Wallis, John W.;Wendl, Michael C.;Zhang, Qunyuan;Durbin, Richard M.;Albers, Cornelis A.;Ayub, Qasim;Balasubramaniam, Senduran;Barrett, Jeffrey C.;Carter, David M.;Chen, Yuan;Conrad, Donald F.;Danecek, Petr;Dermitzakis, Emmanouil T.;Hu, Min;Huang, Ni;Hurles, Matt E.;Jin, Hanjun;Jostins, Luke;Keane, Thomas M.;Keane, Thomas M.;Le, Si Quang;Lindsay, Sarah;Long, Quan;MacArthur, Daniel G.;Montgomery, Stephen B.;Parts, Leopold;Stalker, James;Tyler-Smith, Chris;Walter, Klaudia;Zhang, Yujun;Gerstein, Mark B.;Snyder, Michael;Abyzov, Alexej;Abyzov, Alexej;Balasubramanian, Suganthi;Bjornson, Robert;Du, Jiang;Grubert, Fabian;Habegger, Lukas;Haraksingh, Rajini;Jee, Justin;Khurana, Ekta;Lam, Hugo Y. K.;Leng, Jing;Mu, Xinmeng Jasmine;Urban, Alexander E.;Zhang, Zhengdong;Li, Yingrui;Luo, Ruibang;Marth, Gabor T.;Garrison, Erik P.;Kural, Deniz;Quinlan, Aaron R.;Stewart, Chip;Stromberg, Michael P.;Ward, Alistair N.;Wu, Jiantao;Lee, Charles;Mills, Ryan E.;Shi, Xinghua;McCarroll, Steven A.;Banks, Eric;DePristo, Mark A.;Handsaker, Robert E.;Hartl, Chris;Korn, Joshua M.;Li, Heng;Nemesh, James C.;Sebat, Jonathan;Makarov, Vladimir;Ye, Kenny;Yoon, Seungtai C.;Degenhardt, Jeremiah;Kaganovich, Mark;Clarke, Laura;Smith, Richard E.;Zheng-Bradley, Xiangqun;Korbel, Jan O.;Humphray, Sean;Cheetham, R. Keira;Eberle, Michael;Kahn, Scott;Murray, Lisa;Ye, Kai;De la Vega, Francisco M.;Fu, Yutao;Peckham, Heather E.;Sun, Yongming A.;Batzer, Mark A.;Konkel, Miriam K.;Xiao, Chunlin;Iqbal, Zamin;Desany, Brian;Blackwell, Tom;Snyder, Matthew;Xing, Jinchuan;Eichler, Evan E.;Aksay, Gozde;Alkan, Can;Hajirasouliha, Iman;Hormozdiari, Fereydoun;Kidd, Jeffrey M.;Chen, Ken;Chinwalla, Asif;Ding, Li;McLellan, Mike D.;Wallis, John W.;Hurles, Matt E.;Conrad, Donald F.;Walter, Klaudia;Zhang, Yujun;Gerstein, Mark B.;Snyder, Michael;Abyzov, Alexej;Du, Jiang;Grubert, Fabian;Haraksingh, Rajini;Jee, Justin;Khurana, Ekta;Lam, Hugo Y. K.;Leng, Jing;Mu, Xinmeng Jasmine;Urban, Alexander E.;Zhang, Zhengdong;Gibbs, Richard A.;Bainbridge, Matthew;Challis, Danny;Coafra, Cristian;Dinh, Huyen;Kovar, Christie;Lee, Sandy;Muzny, Donna;Nazareth, Lynne;Reid, Jeff;Sabo, Aniko;Yu, Fuli;Yu, Jin;Marth, Gabor T.;Garrison, Erik P.;Indap, Amit;Leong, Wen Fung;Quinlan, Aaron R.;Stewart, Chip;Ward, Alistair N.;Wu, Jiantao;Cibulskis, Kristian;Fennell, Tim J.;Gabriel, Stacey B.;Garimella, Kiran V.;Hartl, Chris;Shefler, Erica;Sougnez, Carrie L.;Wilkinson, Jane;Clark, Andrew G.;Gravel, Simon;Grubert, Fabian;Clarke, Laura;Flicek, Paul;Smith, Richard E.;Zheng-Bradley, Xiangqun;Sherry, Stephen T.;Khouri, Hoda M.;Paschall, Justin E.;Shumway, Martin F.;Xiao, Chunlin;McVean, Gil A.;Katzman, Sol J.;Abecasis, Goncalo R.;Blackwell, Tom;Mardis, Elaine R.;Dooling, David;Fulton, Lucinda;Fulton, Robert;Koboldt, Daniel C.;Durbin, Richard M.;Balasubramaniam, Senduran;Coffey, Allison;Keane, Thomas M.;MacArthur, Daniel G.;Palotie, Aarno;Scott, Carol;Stalker, James;Tyler-Smith, Chris;Gerstein, Mark B.;Balasubramanian, Suganthi;Chakravarti, Aravinda;Knoppers, Bartha M.;Peltonen, Leena;Abecasis, Goncalo R.;Bustamante, Carlos D.;Gharani, Neda;Gibbs, Richard A.;Jorde, Lynn;Kaye, Jane S.;Kent, Alastair;Li, Taosha;McGuire, Amy L.;McVean, Gil A.;Ossorio, Pilar N.;Rotimi, Charles N.;Su, Yeyang;Toji, Lorraine H.;Tyler-Smith, Chris;Brooks, Lisa D.;Felsenfeld, Adam L.;McEwen, Jean E.;Abdallah, Assya;Juenger, Christopher R.;Clemm, Nicholas C.;Collins, Francis S.;Duncanson, Audrey;Green, Eric D.;Guyer, Mark S.;Peterson, Jane L.;Schafer, Alan J.;Abecasis, Goncalo R.;Altshuler, David L.;Auton, Adam;Brooks, Lisa D.;Durbin, Richard M.;Gibbs, Richard A.;Hurles, Matt E.;McVean, Gil A.
通讯作者：
McVean, Gil A.