Comparison of the Effect of Mindfulness-based Cognitive Therapy Accompanied by Pharmacotherapy With Pharmacotherapy Alone in Treating Dysthymic Patients.
Comparison of the Effect of Mindfulness-based Cognitive Therapy Accompanied by Pharmacotherapy With Pharmacotherapy Alone in Treating Dysthymic Patients.
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DOI：
10.5812/ircmj.8024
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发表时间：
2013-03
影响因子：
0.4
通讯作者：
Naziri G
中科院分区：
文献类型：
--
作者：
Hamidian S;Omidi A;Mousavinasab SM;Naziri G
成人的运动障碍是一种慢性抑郁症，其特征是至少2年的轻度抑郁。与其他形式的抑郁症相比，显著的心理-社会参与，心理-社会功能的更大障碍，以及对这种疾病的首选治疗缺乏明确的研究结果，导致我们在本论文中评估了基于正念的认知疗法(MBCT)与单纯药物治疗相比在治疗恶劣心境方面的有效性。这项研究旨在评估基于正念的认知疗法对一种名为恶劣心境的慢性抑郁症的有效性。这项研究是对转诊于伊朗设拉子医科大学精神科诊所的恶劣心境和双抑郁患者进行的一种干预方法的临床试验。采用方便抽样的方法抽取50例18岁以上患者，随机分为干预组和对照组。对照组只接受药物治疗，干预组在药物治疗的基础上，每周进行8次正念认知治疗，每次治疗2~2.5小时。所有受试者均填写了贝克抑郁量表II和正念五个方面的问卷。使用SPSS统计软件(版本16)、单变量协方差和独立t检验统计方法对数据进行分析。在这项研究中，在人口统计学特征方面，两组之间没有发现显著的差异。在考虑前测的后测变量中，两组之间的平均差异具有统计学意义。试验组参与者在定义的变量方面表现出显著的改善；这一趋势在控制组参与者中没有观察到。本研究结果表明，与单纯药物治疗相比，在治疗恶劣心境患者的药物治疗中加入MBCT可以显著改善患者的抑郁症状和正念技能。
Dysthimia in adults is a chronic depression disorder which is characterized by a mild depression for at least 2 years. Remarkable psycho-social involvements, greater disturbances in psycho-social functions compared to other forms of depression and lack of definite findings about preferred treatment for this disorder led us to evaluate the effectiveness of Mindfulness based cognitive therapy (MBCT) method adjunct to pharmacotherapy compared with pharmachothrapy alone in treating dysthymia in this thesis. This study aimed to evaluate the effectiveness of mindfulness-based cognitive therapy on a chronic type of depression disorder called dysthymia This study is a clinical trial of an interventional method which was carried out on dysthymic and double depressed patients who had referred to psychiatric clinics of Shiraz University of Medical Sciences, Shiraz, Iran. In doing so, 50 patients above the age of 18 were selected through convenience sampling and assigned into intervention and control groups. The control group only received medications while the intervention group in addition to receiving medication, participated in 8 sessions of a mindfulness based cognitive therapy course which was held once a week and each session lasted for 2 to 2.5 hours. All the participants filled out Beck Depression Inventory II and five facet mindfulness questionnaire. The data were analyzed using the SPSS statistical software (version 16) and univariate covariance and independent t test statistical methods. In this study, no statistically significant differences were found between the two groups regarding the demographic characteristics. The mean difference between the two groups was statistically significant for the variables in post-test considering the pre-test. The experimental group participants showed significant improvement in terms of the defined variables; a trend which was not observed in the control group participants. The results of this study show that adding MBCT to pharmacotherapy in treatment of dysthymic patients can cause significant improvement in depression symptoms and mindfulness skills in patients compared to pharmacotherapy alone.
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