Grafting Polymer Brushes by ATRP from Functionalized Poly(ether ether ketone) Microparticles.
Grafting Polymer Brushes by ATRP from Functionalized Poly(ether ether ketone) Microparticles.
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通过 ATRP 从功能化聚醚醚酮微粒接枝聚合物刷。
DOI：
10.1002/pat.5405
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发表时间：
2021-10
影响因子：
3.4
通讯作者：
Matyjaszewski K
中科院分区：
文献类型：
--
作者：
Fu L;Jafari H;Gießl M;Yerneni SS;Sun M;Wang Z;Liu T;Kapil K;Cheng BC;Yu A;Averick SE;Matyjaszewski K
聚醚醚酮(PEEK)是一种具有优异力学性能和化学性能的半结晶热塑性塑料。PEEK表现出高度的耐热、化学和生物降解性。聚醚醚酮作为生物材料应用于骨科和牙科植入物领域，但由于其固有的疏水性和表面惰性，不能有效地支持骨生长。因此，采用新的方法对聚醚醚酮表面进行改性以提高骨结合性能是开发下一代聚合物种植材料的关键。不幸的是，PEEK是一种具有挑战性的材料，既要对其进行修饰，又要对其进行表征，从而阻碍了改善PEEK骨结合的努力。在本文中，我们展示了如何使用表面引发的原子转移自由基聚合(SI-ATRP)来修饰新型PEEK微粒(PMP)。合成了硬核-软壳微球，并用DLS、ATR-IR、XPS和TEM对其进行了表征，表明接枝材料提高了在多种溶剂中的溶解度和稳定性。所发现的表面接枝PMP可用作聚合物-组织界面的相容剂。
Poly(ether ether ketone) (PEEK) is a semi-crystalline thermoplastic with excellent mechanical and chemical properties. PEEK exhibits a high degree of resistance to thermal, chemical, and bio-degradation. PEEK is used as biomaterial in the field of orthopaedic and dental implants; however, due to its intrinsic hydrophobicity and inert surface, PEEK does not effectively support bone growth. Therefore, new methods to modify PEEK’s surface to improve osseointegration are key to next generation polymer implant materials. Unfortunately, PEEK is a challenging material to both modify and subsequently characterize thus stymieing efforts to improve PEEK osseointegration. In this manuscript, we demonstrate how surface-initiated atom transfer radical polymerization (SI-ATRP) can be used to modify novel PEEK microparticles (PMP). The hard core-soft shell microparticles were synthesized and characterized by DLS, ATR-IR, XPS and TEM, indicating the grafted materials increased solubility and stability in a range of solvents. The discovered surface grafted PMP can be used as compatibilizers for the polymer-tissue interface.
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影响因子：
5.5
作者：
Matyjaszewski, K;Miller, PJ;Pakula, T
通讯作者：
Pakula, T
影响因子：
3.2
作者：
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通讯作者：
PORTER, RS
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作者：
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影响因子：
9.7
作者：
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通讯作者：
Gall, Ken