The integrated phenotype.
The integrated phenotype.
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整合表型。
DOI：
10.1093/icb/ics043
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发表时间：
2012
影响因子：
2.6
通讯作者：
C. Murren
中科院分区：
文献类型：
--
作者：
C. Murren
复杂表型的正常运作需要多种性状共同发挥作用。研究复杂性状内部和之间的性状关系，以及它们如何相互作用以作为一个整体发挥作用，对于促进我们对进化发育可塑性的理解至关重要。表型整合是指一个复杂表型的多个性状之间的关系，以及它们与生物体中其他功能单位（模块）之间的关系。在这篇综述中，我总结了植物和动物生物学中表型整合概念的简史。在介绍了包括模块化在内的概念之后，我使用了一种经验性的案例研究方法来强调最近在澄清整合的发展和基因组基础方面的进展。最后，我强调了一些新的方法，基因组和表观遗传扰动，提供承诺，进一步解决表型整合在进化多样化的作用。在表型时代，研究环境中性状关系的基因组和发育变化的研究将塑造我们寻求理解复杂性状进化的下一章。
Proper functioning of complex phenotypes requires that multiple traits work together. Examination of relationships among traits within and between complex characters and how they interact to function as a whole organism is critical to advancing our understanding of evolutionary developmental plasticity. Phenotypic integration refers to the relationships among multiple characters of a complex phenotype, and their relationships with other functional units (modules) in an organism. In this review, I summarize a brief history of the concept of phenotypic integration in plant and animal biology. Following an introduction of concepts, including modularity, I use an empirical case-study approach to highlight recent advance in clarifying the developmental and genomic basis of integration. I end by highlighting some novel approaches to genomic and epigenetic perturbations that offer promise in further addressing the role of phenotypic integration in evolutionary diversification. In the age of the phenotype, studies that examine the genomic and developmental changes in relationships of traits across environments will shape the next chapter in our quest for understanding the evolution of complex characters.
影响因子：
9.5
作者：
Lister, Ryan;Gregory, Brian D.;Ecker, Joseph R.
通讯作者：
Ecker, Joseph R.
影响因子：
2.6
作者：
Ketterson, Ellen D.;Atwell, Jonathan W.;McGlothlin, Joel W.
通讯作者：
McGlothlin, Joel W.
全动物成像，基因功能和斑马鱼现象项目。
影响因子：
4
作者：
Cheng, Keith C.;Xin, Xuying;Clark, Darin P.;La Riviere, Patrick
通讯作者：
La Riviere, Patrick