Evidence for a useful life of more than three years for a polyester-based long-lasting insecticidal mosquito net in Western Uganda.
Evidence for a useful life of more than three years for a polyester-based long-lasting insecticidal mosquito net in Western Uganda.
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乌干达西部的基于聚酯的长期杀虫蚊网超过三年的使用寿命的证据。
DOI：
10.1186/1475-2875-10-299
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发表时间：
2011-10-13
期刊：
影响因子：
3
通讯作者：
Protopopoff N
中科院分区：
文献类型：
--
作者：
Kilian A;Byamukama W;Pigeon O;Gimnig J;Atieli F;Koekemoer L;Protopopoff N
长效驱虫蚊帐现已成为预防疟疾的标准用品。然而，只应使用世界卫生组织建议公众使用的产品，而这项评估包括实地使用三年后的净效果评估。给出了一种聚酯基产品Interceptor®的结果。在5个村庄，随机分发了190个长效驱虫蚊帐和90个按传统方法用25毫克/平方米的甲型氯氰菊酯杀虫剂处理过的蚊帐，供家庭使用。在基线家庭调查之后，每六个月进行一次蚊帐调查，以了解蚊帐的使用、洗涤习惯和实际状况。在6个月、12个月、24个月、36个月和42个月后收集随机选择的蚊帐，并测试剩余杀虫剂含量以及击倒和杀死传播疟疾的蚊子的能力。在三年半的观察期间，只有16个蚊帐失访，估计三年后的损耗率为12%，3.5年后为20%。定期使用蚊帐，平均每年清洗1.5次。三年半后，29%的蚊帐仍处于良好状态，而13%的蚊帐严重撕裂，LLIN和对照蚊帐之间没有差异。传统处理的蚊帐很快失去杀虫剂，24个月后，只有7%的原始剂量（1.6毫克/平方米）。长效驱虫蚊帐中的甲型氯氰菊酯基线中位浓度为194.5毫克/平方米或目标剂量的97%，净变异之间和净变异范围内分别为11%和4%（相对标准偏差）。在长效杀虫剂网络中，使用三年后甲型氯氰菊酯残留量为73.8毫克/平方米，使用三年半后为56.2毫克/平方米，分别有94%和81%的长效杀虫剂网络残留量仍大于15毫克/平方米。生物测定的最佳有效性（≥95% 60分钟击倒或≥ 80% 24小时死亡率）在三年后的83%和三年半后的71%中发现。在乌干达西部的条件下，经过测试的长效驱虫蚊帐Interceptor®符合世卫组织第三阶段评价的标准，根据使用寿命的初步标准，该产品估计平均使用三至四年。
Long-lasting insecticidal nets (LLIN) are now standard for the prevention of malaria. However, only products with recommendation for public use from the World Health Organization should be used and this evaluation includes the assessment of net effectiveness after three years of field use. Results for one of the polyester-based products, Interceptor® is presented. In five villages, 190 LLIN and 90 nets conventionally treated with the insecticide alpha-cypermethrin at 25 mg/m2 were distributed randomly and used by the families. Following a baseline household survey a net survey was carried out every six months to capture use, washing habits and physical condition of the nets. Randomly selected nets were collected after 6, 12, 24, 36 and 42 months and tested for remaining insecticide content and ability to knock-down and kill malaria transmitting mosquitoes. During the three and a half years of observation only 16 nets were lost to follow-up resulting in an estimated attrition rate of 12% after three and 20/% after 3.5 years. Nets were used regularly and washed on average 1.5 times per year. After three and a half years 29% of the nets were still in good condition while 13% were seriously torn with no difference between the LLIN and control nets. The conventionally treated nets quickly lost insecticide and after 24 months only 7% of the original dose remained (1.6 mg/m2). Baseline median concentration of alpha-cypermethrin for LLIN was 194.5 mg/m2 or 97% of the target dose with between and within net variation of 11% and 4% respectively (relative standard deviation). On the LLIN 73.8 mg/m2 alpha-cypermethrin remained after three years of use and 56.2 mg/m2 after three and a half and 94% and 81% of the LLIN still had > 15 mg/m2 left respectively. Optimal effectiveness in bio-assays (≥95% 60 minute knock-down or ≥ 80% 24 hour mortality) was found in 83% of the sampled LLIN after three and 71% after three and a half years. Under conditions in Western Uganda the tested long-lasting insecticidal net Interceptor® fulfilled the criteria for phase III of WHO evaluations and, based on preliminary criteria of the useful life, this product is estimated to last on average between three and four years.
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影响因子：
3.3
作者：
Maxwell, CA;Msuya, E;Curtis, CF
通讯作者：
Curtis, CF
影响因子：
1.9
作者：
Jawara, M;McBeath, J;Greenwood, BM
通讯作者：
Greenwood, BM
DOI：
10.4269/ajtmh.2007.77.243
发表时间：
2007-12-01
影响因子：
3.3
作者：
Smith, Stephen C.;Joshi, Uday B.;Aapore, Thomas
通讯作者：
Aapore, Thomas
影响因子：
1.9
作者：
Adams, KJ;Chavasse, DC;Curtis, CF
通讯作者：
Curtis, CF
影响因子：
3.3
作者：
Jawara, M;Pinder, M;Rowley, J
通讯作者：
Rowley, J