Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence.

Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence.
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DOI:
10.1007/s11892-023-01515-1
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发表时间:
2023-08
影响因子:
4.2
通讯作者:
Yeh, Hsin-Chieh
Yeh, Hsin-Chieh
中科院分区:
医学2区
文献类型:
--
作者:
Wong, Rachel;Lam, Emily;Bramante, Carolyn T. T.;Johnson, Steven G. G.;Reusch, Jane;Wilkins, Kenneth J. J.;Yeh, Hsin-Chieh

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多项研究报告了SARS-CoV-2感染后糖尿病的发病率增加。考虑到糖尿病的潜在全球负担增加,了解SARS-CoV-2在糖尿病流行病学中的作用非常重要。我们的目的是审查与COVID-19感染后发生糖尿病风险有关的证据。与未感染SARS-CoV-2的患者相比,发生糖尿病的风险增加了约60%。与非COVID-19呼吸道感染相比,风险也增加了,这表明SARS-CoV-2介导的机制,而不是呼吸道疾病后的一般发病率。关于SARS-CoV-2感染与T1 D之间的联系,证据好坏参半。SARS-CoV-2感染与T2 D风险升高相关,但尚不清楚糖尿病事件是否随时间持续或随时间推移严重程度不同。SARS-CoV-2感染与糖尿病发病风险增加有关。未来的研究应评估疫苗接种、病毒变异以及影响风险的患者和治疗相关因素。
Multiple studies report an increased incidence of diabetes following SARS-CoV-2 infection. Given the potential increased global burden of diabetes, understanding the effect of SARS-CoV-2 in the epidemiology of diabetes is important. Our aim was to review the evidence pertaining to the risk of incident diabetes after COVID-19 infection. Incident diabetes risk increased by approximately 60% compared to patients without SARS-CoV-2 infection. Risk also increased compared to non-COVID-19 respiratory infections, suggesting SARS-CoV-2-mediated mechanisms rather than general morbidity after respiratory illness. Evidence is mixed regarding the association between SARS-CoV-2 infection and T1D. SARS-CoV-2 infection is associated with an elevated risk of T2D, but it is unclear whether the incident diabetes is persistent over time or differs in severity over time. SARS-CoV-2 infection is associated with an increased risk of incident diabetes. Future studies should evaluate vaccination, viral variant, and patient- and treatment-related factors that influence risk.
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