Classification of crystallization outcomes using deep convolutional neural networks.
Classification of crystallization outcomes using deep convolutional neural networks.
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DOI:
10.1371/journal.pone.0198883
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发表时间:
2018
期刊:
影响因子:
3.7
通讯作者:
Wilson J
中科院分区:
文献类型:
--
作者:
Bruno AE;Charbonneau P;Newman J;Snell EH;So DR;Vanhoucke V;Watkins CJ;Williams S;Wilson J
The Machine Recognition of Crystallization Outcomes (MARCO) initiative has assembled roughly half a million annotated images of macromolecular crystallization experiments from various sources and setups. Here, state-of-the-art machine learning algorithms are trained and tested on different parts of this data set. We find that more than 94% of the test images can be correctly labeled, irrespective of their experimental origin. Because crystal recognition is key to high-density screening and the systematic analysis of crystallization experiments, this approach opens the door to both industrial and fundamental research applications.
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DOI:
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发表时间:
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期刊:
Journal of structural and functional genomics
影响因子:
--
作者:
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通讯作者:
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期刊:
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影响因子:
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作者:
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