Illness management and recovery: Clinical outcomes of a randomized clinical trial in community mental health centers.
Illness management and recovery: Clinical outcomes of a randomized clinical trial in community mental health centers.
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DOI：
10.1371/journal.pone.0194027
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Eplov LF
中科院分区：
文献类型：
--
作者：
Dalum HS;Waldemar AK;Korsbek L;Hjorthøj C;Mikkelsen JH;Thomsen K;Kistrup K;Olander M;Lindschou J;Nordentoft M;Eplov LF
疾病管理和康复（IMR）是一种以康复为导向的心理社会干预措施。该方案已在不同的环境中进行了评估;然而，IMR效果的证据仍然不足。本试验的目的是调查丹麦精神分裂症或双相情感障碍患者中IMR项目与常规治疗相比的获益和危害。该试验设计为一项随机、评估者设盲、多中心临床试验，旨在研究IMR方案与常规治疗的比较。198名被诊断为精神分裂症或双相情感障碍的人参加了研究。主要结局是干预结束时的总体功能评估（GAF-F），次要和探索性结局包括症状严重程度和服务利用。IMR对功能，症状，物质使用或服务利用没有显着影响。这项随机试验为IMR的证据基础做出了贡献，为其结论提供了坚实的方法学基础;然而，该试验存在一些重要的局限性。需要更多的研究来确定IMR的有效性。
Illness Management and Recovery (IMR) is a psychosocial intervention with a recovery-oriented approach. The program has been evaluated in different settings; however evidence for the effects of IMR is still deficient. The aim of this trial was to investigate the benefits and harms of the IMR program compared with treatment as usual in Danish patients with schizophrenia or bipolar disorder. The trial was designed as a randomized, assessor-blinded, multi-center, clinical trial investigating the IMR program compared with usual treatment. 198 people diagnosed with schizophrenia or bipolar disorder participated. The primary outcome was the Global Assessment of Functioning (GAF-F) at the end of intervention and the secondary and explorative outcomes included severity of symptoms and service utilization. IMR had no significant effect on functioning, symptoms, substance use or service utilization. This randomized trial contributes to the evidence base of IMR by providing a methodological solid base for its conclusions; however the trial has some important limitations. More research is needed to get a firm answer on the effectiveness of the IMR.
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DOI：
10.1016/s0197-2456(98)00037-3
发表时间：
1998-12-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
Dupont, WD;Plummer, WD
通讯作者：
Plummer, WD
影响因子：
3.8
作者：
Hasson-Ohayon, Ilanit;Roe, David;Kravetz, Shlomo
通讯作者：
Kravetz, Shlomo
影响因子：
7.3
作者：
Pedersen, Geir;Karterud, Sigmund
通讯作者：
Karterud, Sigmund
DOI：
10.1056/nejmsr1203730
发表时间：
2012-10-04
期刊：
The New England journal of medicine
影响因子：
--
作者：
Little RJ;D'Agostino R;Cohen ML;Dickersin K;Emerson SS;Farrar JT;Frangakis C;Hogan JW;Molenberghs G;Murphy SA;Neaton JD;Rotnitzky A;Scharfstein D;Shih WJ;Siegel JP;Stern H
通讯作者：
Stern H
影响因子：
2.5
作者：
Dalum HS;Korsbek L;Mikkelsen JH;Thomsen K;Kistrup K;Olander M;Hansen JL;Nordentoft M;Eplov LF
通讯作者：
Eplov LF