Development of antibody surrogates for the treatment of cancers and autoimmune disease.
Development of antibody surrogates for the treatment of cancers and autoimmune disease.
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DOI：
10.1016/j.cbpa.2010.07.002
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发表时间：
2010-12
影响因子：
7.8
通讯作者：
Kodadek, Thomas
中科院分区：
文献类型：
--
作者：
Kodadek, Thomas
Some therapeutic monoclonal antibodies function by focusing the killing power of the immune system on particular cellular targets, a process known as antibody-dependent cell-mediated cytotoxicity (ADCC). There is considerable interest in developing small molecules therapeutics that utilize this mechanism of action and so act as a kind of antibody surrogate. Progress and challenges in this interesting field are reviewed here.
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影响因子：
9.7
作者：
Oyama, T;Sykes, KF;Brown, KC
通讯作者：
Brown, KC
影响因子：
15
作者：
Udugamasooriya, D. Gomika;Dineen, Sean P.;Kodadek, Thomas
通讯作者：
Kodadek, Thomas
影响因子：
15
作者：
Murelli, Ryan P.;Zhang, Andrew X.;Michel, Julien;Jorgensen, William L.;Spiegel, David A.
通讯作者：
Spiegel, David A.
DOI：
10.1056/nejmoa0706383
发表时间：
2008-02-14
期刊：
The New England journal of medicine
影响因子：
--
作者：
Hauser, Stephen L;Waubant, Emmanuelle;Smith, Craig H
通讯作者：
Smith, Craig H
影响因子：
--
作者：
Gocke, Anne R.;Udugamasooriya, D. Gomika;Kodadek, Thomas
通讯作者：
Kodadek, Thomas