Positron emission tomography-computed tomography standardized uptake values in clinical practice and assessing response to therapy.
Positron emission tomography-computed tomography standardized uptake values in clinical practice and assessing response to therapy.
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DOI:
10.1053/j.sult.2010.10.001
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发表时间:
2010-12
期刊:
影响因子:
--
通讯作者:
Fletcher JW
中科院分区:
文献类型:
--
作者:
Kinahan PE;Fletcher JW
The use of standardized uptake values (SUVs) is now common place in clinical FDG-PET/CT oncology imaging, and has a specific role in assessing patient response to cancer therapy. Ideally, the use of SUVs removes variability introduced by differences in patient size and the amount of injected FDG. However, in practice there are several sources of bias and variance that are introduced in the measurement of FDG uptake in tumors and also in the conversion of the image count data to SUVs. The overall imaging process is reviewed and estimates of the magnitude of errors, where known, are given. Recommendations are provided for best practices in improving SUV accuracy.
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