Causes of deaths in neonates and children aged 1-59 months in Nigeria: verbal autopsy findings of 2019 Verbal and Social Autopsy study.
Causes of deaths in neonates and children aged 1-59 months in Nigeria: verbal autopsy findings of 2019 Verbal and Social Autopsy study.
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DOI：
10.1186/s12889-022-13507-z
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发表时间：
2022-06-06
影响因子：
4.5
通讯作者：
Franca-Koh, Ana Claudia
中科院分区：
文献类型：
--
作者：
Odejimi, Adeyinka;Quinley, John;Eluwa, George Ikechi;Kunnuji, Michael;Wammanda, Robinson Daniel;Weiss, William;James, Femi;Bello, Mustapha;Ogunlewe, Adenike;King, Rebekah;Franca-Koh, Ana Claudia
尼日利亚是世界上五岁以下儿童死亡率最高的国家之一。查明这些死亡的原因对于政策文件的修改、设计和实施适当的干预措施以减少这些死亡至关重要。这项研究旨在提供2013-2018年期间尼日利亚五岁以下儿童死亡原因的国家和地区估计数。我们对2018年尼日利亚人口与健康调查（NDHS）中确定的948名新生儿和2，127名1-59个月儿童的死亡原因进行了回顾性调查。口头尸检询问了最后一次患病期间的体征和症状。采用医生编码口头尸检（PCVA）和专家算法口头尸检（EAVA）方法分配所有病例的直接和潜在死亡原因。在分析中，采用抽样权重以适应非比例分配。男童占新生儿死亡人数的56%，占1-59个月死亡人数的51.5%。5岁以下儿童死亡率中约有四分之一是新生儿死亡，其中50%的新生儿死亡发生在分娩后48小时内。总体而言，84%的5岁以下儿童死亡发生在北方地缘政治区域。根据病例分析的两种方法，新生儿感染（败血症，肺炎和脑膜炎）占新生儿死亡的44%，其次是产时损伤（PCVA：21%与EAVA：29%）。1-59个月儿童死亡的三个主要原因是疟疾（PCVA：23% vs. EAVA：35%）、腹泻（PCVA：17% vs. EAVA：23%）和肺炎（PCVA：10% vs. EAVA：12%）。在西北部，大多数5岁以下儿童（1-59个月）死亡的记录，腹泻是主要的死亡原因（PCVA：24.3%，EAVA：30%）。新生儿和1-59个月儿童死亡的原因在北方和南方各地区各不相同。该研究报告通过按区域寻找具体的死亡原因，提供了重要的信息，可能有助于规划适当的干预措施，以大幅减少尼日利亚五岁以下儿童的死亡。在线版本包含补充材料，可通过10.1186/s12889-022-13507-z获得。
Nigeria has one of the highest under-five mortality rates in the world. Identifying the causes of these deaths is crucial to inform changes in policy documents, design and implementation of appropriate interventions to reduce these deaths. This study aimed to provide national and zonal-level estimates of the causes of under-five death in Nigeria in the 2013–2018 periods. We conducted retrospective inquiries into the cause of deaths of 948 neonates and 2,127 children aged 1–59 months as identified in the 2018 Nigeria Demographic and Health Survey (NDHS). The verbal autopsy asked about signs and symptoms during the final illness. The Physician Coded Verbal Autopsy (PCVA) and Expert Algorithm Verbal Autopsy (EAVA) methods were employed to assign the immediate and underlying cause of deaths to all cases. For the analysis, sampling weights were applied to accommodate non-proportional allocation. Boys accounted for 56 percent of neonatal deaths and 51.5 percent of the 1–59-months old deaths. About one-quarter of under-5 mortality was attributed to neonatal deaths, and 50 percent of these neonatal deaths were recorded within 48 h of delivery. Overall, 84 percent of the under-5 deaths were in the northern geopolitical zones. Based on the two methods for case analysis, neonatal infections (sepsis, pneumonia, and meningitis) were responsible for 44 percent of the neonatal deaths, followed by intrapartum injury (PCVA: 21 percent vs. EAVA: 29 percent). The three main causes of death in children aged 1–59 months were malaria (PCVA: 23 percent vs. EAVA: 35 percent), diarrhoea (PCVA: 17 percent vs. EAVA: 23 percent), and pneumonia (PCVA: 10 percent vs. EAVA: 12 percent). In the North West, where the majority of under-5 (1–59 months) deaths were recorded, diarrhoea was the main cause of death (PCVA: 24.3 percent vs. EAVA: 30 percent). The causes of neonatal and children aged 1–59 months deaths vary across the northern and southern regions. By homing on the specific causes of mortality by region, the study provides crucial information that may be useful in planning appropriately tailored interventions to significantly reduce under-five deaths in Nigeria. The online version contains supplementary material available at 10.1186/s12889-022-13507-z.
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影响因子：
5.2
作者：
Onwujekwe O;Ensor T;Ogbozor P;Okeke C;Ezenwaka U;Hicks JP;Etiaba E;Uzochukwu B;Ebenso B;Mirzoev T
通讯作者：
Mirzoev T
影响因子：
3.7
作者：
Halim, Abdul;Dewez, Juan Emmanuel;van den Broek, Nynke
通讯作者：
van den Broek, Nynke
影响因子：
7.2
作者：
Kalter, Henry D.;Roubanatou, Abdoulaye-Mamadou;Black, Robert E.
通讯作者：
Black, Robert E.
DOI：
10.1073/pnas.0800221105
发表时间：
2008-04-01
影响因子：
11.1
作者：
Drevenstedt, Greg L.;Crimmins, Eileen M.;Finch, Caleb E.
通讯作者：
Finch, Caleb E.
DOI：
10.1038/sj.jp.7211084
发表时间：
2004-05-01
期刊：
Journal of perinatology : official journal of the California Perinatal Association
影响因子：
--
作者：
Campbell, Oona;Gipson, Reginald;Mohsen, Lamiaa
通讯作者：
Mohsen, Lamiaa