Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis.
Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis.
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精神障碍对主动结核病治疗结果的影响:系统评价和荟萃分析。
DOI:
10.5588/ijtld.20.0458
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发表时间:
2020-12-01
期刊:
影响因子:
--
通讯作者:
Sweetland AC
中科院分区:
文献类型:
--
作者:
Lee G;Scuffell J;Galea JT;Shin SS;Magill E;Jaramillo E;Sweetland AC
Comorbid mental disorders in patients with tuberculosis (TB) may exacerbate TB treatment outcomes. We systematically reviewed current evidence on the association between mental disorders and TB outcomes. We searched eight databases for studies published from 1990-2018 that compared TB treatment outcomes among patients with and without mental disorders. We excluded studies that did not systematically assess mental disorders and studies limited to substance use. We extracted study and patient characteristics and effect measures and performed a meta-analysis using random-effects models to calculate summary odds ratios (OR) with 95% confidence intervals (CI). Of 7,687 studies identified, ten were included in the systematic review and nine in the meta-analysis. Measurement of mental disorders and TB outcomes were heterogeneous across studies. The pooled association between mental disorders and any poor outcome, loss to follow-up, and non-adherence were OR 2.13 (95% CI: 0.85-5.37), 1.90 (0.33-10.91), and 1.60 (0.81-3.02), respectively. High statistical heterogeneity was present. Our review suggests that mental disorders in TB patients increase the risk of poor TB outcomes, but pooled estimates were imprecise due to small number of eligible studies. Integration of psychological and TB services might improve TB outcomes and progress towards TB elimination.
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DOI:
10.1183/09031936.00193413
发表时间:
2014-06
期刊:
The European respiratory journal
影响因子:
--
作者:
Tanimura T;Jaramillo E;Weil D;Raviglione M;Lönnroth K
通讯作者:
Lönnroth K
影响因子:
4.5
作者:
Naidoo P;Peltzer K;Louw J;Matseke G;McHunu G;Tutshana B
通讯作者:
Tutshana B
DOI:
10.1086/594126
发表时间:
2009-01-01
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
作者:
Deiss RG;Rodwell TC;Garfein RS
通讯作者:
Garfein RS
影响因子:
4.9
作者:
Eze-Nliam CM;Thombs BD;Lima BB;Smith CG;Ziegelstein RC
通讯作者:
Ziegelstein RC
DOI:
10.5588/ijtld.16.0584
发表时间:
2017-08-01
影响因子:
4
作者:
Sweetland, A. C.;Kritski, A.;Wainberg, M. L.
通讯作者:
Wainberg, M. L.