Linear Ubiquitination of RIPK1 on Lys612 Regulates Systemic Inflammation via Preventing Cell Death
Linear Ubiquitination of RIPK1 on Lys612 Regulates Systemic Inflammation via Preventing Cell Death
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Lys612 上的 RIPK1 线性泛素化通过防止细胞死亡来调节全身炎症
DOI:
10.4049/jimmunol.2100299
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发表时间:
2021-06
影响因子:
4.4
通讯作者:
Xin Lin
中科院分区:
文献类型:
--
作者:
Hailin Tu;Yong Tang;Jie Zhang;Liqing Cheng;Donghyun Joo;Xueqiang Zhao;Xin Lin
Receptor-interacting protein kinase-1 (RIPK1) is a master regulator of the TNF-α–induced cell death program. The function of RIPK1 is tightly controlled by posttranslational modifications, including linear ubiquitin chain assembly complex–mediated linear
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