Highly Water-soluble and Surface Charge-tunable Fluorescent Fullerene Nanoparticles: Facile Fabrication and Cellular Imaging

Highly Water-soluble and Surface Charge-tunable Fluorescent Fullerene Nanoparticles: Facile Fabrication and Cellular Imaging
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高水溶性和表面电荷可调的荧光富勒烯纳米颗粒:易于制造和细胞成像

DOI:
10.1016/j.electacta.2016.03.198
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发表时间:
2016-05
影响因子:
6.6
通讯作者:
Fan Hong
Fan Hong
中科院分区:
材料科学2区
文献类型:
--
作者:
Xie Rongbin;Wang Zifei;Yu Hongtao;Fan Zetan;Yuan Fanglong;Li Yunchao;Li Xiaohong;Fan Louzhen;Fan Hong

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通过研磨和水热处理合成了具有强绿色发光的水溶性、表面电荷可调的胺功能化多羟基富勒烯纳米粒子。纳米颗粒的量子产率高达17%,这是荧光富勒烯材料记录的最高值。具有高表面电荷的胺官能化的多羟基化富勒烯纳米颗粒被发现很容易渗透到乳腺癌细胞、HeLa细胞和心脏祖细胞干细胞中,为其生物医学应用开辟了巨大的机会。
Water-soluble and surface charge-tunable amine-functionalized polyhydroxylated fullerene nanoparticles with a strong green emission were synthesized by grinding and hydrothermal treatment. The quantum yield of the nanoparticles was as high as 17%, which is the highest value recorded for fluorescent fullerene materials. The amine-functionalized polyhydroxylated fullerene nanoparticles with high surface charge were found to easily penetrate into breast cancer cells, HeLa cells and cardiac progenitor stem cells, opening up great opportunities for their bio-medical applications.
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