Dual-Pathway sequences for MR thermometry: When and where to use them.
Dual-Pathway sequences for MR thermometry: When and where to use them.
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DOI：
10.1002/mrm.26177
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发表时间：
2017-03
影响因子：
3.3
通讯作者：
Madore, Bruno
中科院分区：
文献类型：
--
作者：
Ciris, Pelin Aksit;Cheng, Cheng-Chieh;Mei, Chang-Sheng;Panych, Lawrence P.;Madore, Bruno
关键词：
为了提高磁共振测温中的温度噪声比（TNR），提出了双路径序列。目前的工作确定了这些所谓的“PSIF-FISP”序列可能给各种器官和组织带来多大的改善。模拟和TNR计算通过解析方程、幻影、腹部和脑部扫描进行验证。在翻转角(FA) = 1 ~ 85°，TR = 6 ~ 60ms，灰质、白质、子宫颈、子宫内膜、肌层、前列腺、肾髓质和皮质、骨髓、胰腺、脾脏、肌肉和肝脏组织中，计算PSIF-FISP与双fisp参考标准的相对tnr。在大多数测试的TR和FA设置中，PSIF-FISP在肾脏，骨盆，脾脏或灰质中的TNR优于PSIF-FISP，并且在较短的TR中获益增加。PSIF-FISP在其他组织（如肝脏、肌肉、胰腺）的TNR优于其他组织（仅在短TR设置（20ms或更短）时）。PSIF-FISP的TNR效益随着FA的增加而略有增加，而随着TR的降低而显著增加。可实现高达2-3倍的TR降低和20%的TNR增加。在任何给定的组织中，由于松弛率的变化，TNR性能有望随着加热而进一步改善。与标准GRE序列相比，双通路PSIF-FISP可以提高TNR和采集速度，但最佳采集参数取决于组织。
Dual-pathway sequences have been proposed to help improve the temperature-to-noise-ratio (TNR) in MR thermometry. The present work establishes how much of an improvement these so-called ‘PSIF-FISP’ sequences may bring in various organs and tissues. Simulations and TNR calculations were validated against analytical equations, phantom, abdomen and brain scans. Relative TNRs for PSIF-FISP, as compared to a dual-FISP reference standard, were calculated for flip angle (FA) = 1 to 85° and TR = 6 to 60ms, for gray matter, white matter, cervix, endometrium, myometrium, prostate, kidney medulla and cortex, bone marrow, pancreas, spleen, muscle, and liver tissues. PSIF-FISP was TNR superior in the kidney, pelvis, spleen or gray matter at most tested TR and FA settings, and benefits increased at shorter TRs. PSIF-FISP was TNR superior in other tissues, e.g. liver, muscle, pancreas, for only short TR settings (20ms or less). The TNR benefits of PSIF-FISP increased slightly with FA, and strongly with decreasing TR. Up to 2-3 fold reductions in TR with 20% TNR gains were achievable. In any given tissue, TNR performance is expected to further improve with heating, due to changes in relaxation rates. Dual-pathway PSIF-FISP can improve TNR and acquisition speed over standard GRE sequences, but optimal acquisition parameters are tissue dependent.
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影响因子：
3.3
作者：
BRUDER, H;FISCHER, H;DEIMLING, M
通讯作者：
DEIMLING, M
影响因子：
2.2
作者：
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影响因子：
3.8
作者：
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3.3
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影响因子：
4.6
作者：
PARKER, DL
通讯作者：
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