Bibliometric Analysis of Global Research on Cancer Photodynamic Therapy: Focus on Nano-Related Research.

Bibliometric Analysis of Global Research on Cancer Photodynamic Therapy: Focus on Nano-Related Research.
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DOI:
10.3389/fphar.2022.927219
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发表时间:
2022
影响因子:
5.6
通讯作者:
Wu, Haiyang
Wu, Haiyang
中科院分区:
医学2区
文献类型:
--
作者:
Cheng, Kunming;Guo, Qiang;Shen, Zefeng;Yang, Weiguang;Wang, Yulin;Sun, Zaijie;Wu, Haiyang

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越来越多的研究表明,光动力疗法(PDT)是肿瘤学的重要治疗策略,并已成为近年来的热门话题。尽管已经发表了大量与癌症PDT(CPDT)相关的论文,但尚未进行文献计量研究来总结研究格局,并突出该领域的研究趋势和热点。本研究收集了 Web of Science 核心合集中 2000 年至 2021 年间发布的 5,804 条 CPDT 记录。使用 VOSviewer、CiteSpace 和一个在线平台进行文献计量分析和可视化。年度发表和引用结果揭示了过去 22 年中显着的增长趋势。中国和美国是该领域的主要推动力,占出版物总量的56.24%。中国科学院是最多产的机构。 《光诊断和光动力疗法》以及《光化学和光生物学》分别是生产力最高和共同被引用最多的期刊。所有关键词均分为纳米材料技术、临床应用、机理和光敏剂研究四类。 “基于纳米技术的PDT”和“增强型PDT”是当前的研究热点。除了“纳米球”、“纳米粒子”、“纳米材料”、“纳米平台”、“纳米医学”、“金纳米粒子”等纳米相关主题外,“光热疗法”、“金属有机框架”、“检查点封锁”、“肿瘤微环境”、“前药”等主题也值得进一步关注。
A growing body of research has illuminated that photodynamic therapy (PDT) serves as an important therapeutic strategy in oncology and has become a hot topic in recent years. Although numerous papers related to cancer PDT (CPDT) have been published, no bibliometric studies have been conducted to summarize the research landscape, and highlight the research trends and hotspots in this field. This study collected 5,804 records on CPDT published between 2000 and 2021 from Web of Science Core Collection. Bibliometric analysis and visualization were conducted using VOSviewer, CiteSpace, and one online platform. The annual publication and citation results revealed significant increasing trends over the past 22 years. China and the United States, contributing 56.24% of the total publications, were the main driving force in this field. Chinese Academy of Sciences was the most prolific institution. Photodiagnosis and Photodynamic Therapy and Photochemistry and Photobiology were the most productive and most co-cited journals, respectively. All keywords were categorized into four clusters including studies on nanomaterial technology, clinical applications, mechanism, and photosensitizers. “nanotech-based PDT” and “enhanced PDT” were current research hotspots. In addition to several nano-related topics such as “nanosphere,” “nanoparticle,” “nanomaterial,” “nanoplatform,” “nanomedicine” and “gold nanoparticle,” the following topics including “photothermal therapy,” “metal organic framework,” “checkpoint blockade,” “tumor microenvironment,” “prodrug” also deserve further attention in the near future.
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