Modeling and reasoning with qualitative comparative clinical knowledge
Modeling and reasoning with qualitative comparative clinical knowledge
复制标题
利用定性比较临床知识进行建模和推理
DOI:
10.1002/int.20445
复制
发表时间:
2011
影响因子:
7
通讯作者:
Ma J
中科院分区:
文献类型:
--
作者:
Ma J
The number of clinical trials reports is increasing rapidly due to a large number of clinical trials being conducted; it, therefore, raises an urgent need to utilize the clinical knowledge contained in the clinical trials reports. In this paper, we focus on the qualitative knowledge instead of quantitative knowledge. More precisely, we aim to model and reason with the qualitative comparison (QC for short) relations which consider qualitatively how strongly one drug/therapy is preferred to another in a clinical point of view. To this end, first, we formalize the QC relations, introduce the notions of QC language, QC base, and QC profile; second, we propose a set of induction rules for the QC relations and provide grading interpretations for the QC bases and show how to determine whether a QC base is consistent. Furthermore, when a QC base is inconsistent, we analyze how to measure inconsistencies among QC bases, and we propose different approaches to merging multiple QC bases. Finally, a case study on lowering intraocular pressure is conducted to illustrate our approaches. © 2010 Wiley Periodicals, Inc.
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DOI:
--
发表时间:
1993
期刊:
International Joint Conference on Artificial Intelligence
影响因子:
--
作者:
P. Dague
通讯作者:
P. Dague
DOI:
--
发表时间:
1988
期刊:
Artificial Intelligence in Engineering
影响因子:
--
作者:
Jean;O. Raiman
通讯作者:
O. Raiman
影响因子:
2.7
作者:
G. Lip
通讯作者:
G. Lip
影响因子:
3.9
作者:
Arcieri, E. S.;Pierre Filho, P. T. P.;Costa, V. P.
通讯作者:
Costa, V. P.
影响因子:
3.2
作者:
P. Denis;R. Launois;M. Devaux;G. Berdeaux
通讯作者:
G. Berdeaux