Absence of the 9-bp Deletion of Mitochondrial DNA in Pre-Hispanic Inhabitants of Argentina
Absence of the 9-bp Deletion of Mitochondrial DNA in Pre-Hispanic Inhabitants of Argentina
复制标题
阿根廷前西班牙裔居民线粒体 DNA 9 bp 缺失缺失
DOI：
10.1353/hub.2001.0050
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
A. Marcellino
中科院分区：
文献类型：
--
作者：
D. Demarchi;Graciela M Panzetta;S. Colantonio;A. Marcellino
我们调查了从阿根廷几个考古遗址和背景中发现的人类遗骸中线粒体DNA V区9碱基对(BP)缺失的发生率。在分析的34个样本中，有24个产生了清晰的扩增结果的DNA提取。所有这些个体都携带两个9BP的重复序列，其中一个在一些亚洲血统的个体中被证明是缺失的，并定义了线粒体谱系B。尽管该地区的大多数现代美洲印第安人群体都表现出高频的缺失，但南美洲古代群体中没有9-BP缺失似乎是规则，而不是例外，正如几项涉及灭绝群体的研究所报道的那样。到目前为止收集的证据表明，南美洲这一地区最早的定居者并没有携带线粒体血统B。
We investigated the incidence of the Region V mitochondrial DNA 9-base-pair (bp) deletion from human remains recovered from several archaeological sites and contexts throughout Argentina. Of the 34 samples analyzed, 24 yielded DNA extractions that gave clear amplification results. All of the individuals carried two repeats of the 9 bp, one of which has been shown to be deleted in some individuals of Asian origin and defines mitochondrial lineage B. Although most of the modern Amerindian groups in the region exhibit the deletion in high frequencies, the absence of the 9-bp deletion among ancient populations of South America seems to be the rule rather than the exception, as was reported by several studies involving extinct populations. The evidence gathered until now suggests that the earliest settlers of this region of South America did not carry mitochondrial lineage B.
影响因子：
3.3
作者：
S. Ballinger;T. Schurr;A. Torroni;Y. Gan;J. A. Hodge;K. Hassan;K. H. Chen;Douglas C. Wallace
通讯作者：
S. Ballinger;T. Schurr;A. Torroni;Y. Gan;J. A. Hodge;K. Hassan;K. H. Chen;Douglas C. Wallace
四个美洲原住民 mtDNA 的亚洲亲缘关系和大陆辐射。
影响因子：
9.8
作者：
Torroni,A;Schurr,TG;Cabell,MF;Brown,MD;Neel,JV;Larsen,M;Smith,DG;Vullo,CM;Wallace,DC
通讯作者：
Wallace,DC
DOI：
10.1073/pnas.77.11.6715
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
GILES, RE;BLANC, H;WALLACE, DC
通讯作者：
WALLACE, DC