Optimizing weight gain in pregnancy to prevent obesity in women and children.
Optimizing weight gain in pregnancy to prevent obesity in women and children.
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DOI：
10.1111/j.1463-1326.2011.01489.x
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发表时间：
2012-03
期刊：
影响因子：
--
通讯作者：
Oken E
中科院分区：
文献类型：
--
作者：
Herring SJ;Rose MZ;Skouteris H;Oken E
怀孕现在被认为是育龄妇女新发或持续性肥胖的一个重要风险因素。高妊娠期体重增加是母亲怀孕后超重或肥胖的最强预测因子。越来越多的证据还表明，妊娠期体重增加的高和低都与儿童肥胖风险增加独立相关，这表明生命早期发生的影响有助于肥胖的发生。针对这些数据，美国医学研究所（IOM）在2009年修订了妊娠期体重增加指南，这是近二十年来的第一次。然而，只有不到三分之一的孕妇达到了指南建议的增益，大多数孕妇的增益高于IOM建议的水平。到目前为止，优化怀孕体重增加的干预措施取得了好坏参半的成功。在本文中，我们总结了人类和动物研究的证据，将妊娠期营养过剩和营养不足与母亲和儿童肥胖联系起来。此外，我们还讨论了已发表的试验和正在进行的干预措施，以实现适当的妊娠期体重增加作为预防妇女及其子女肥胖的策略。
Pregnancy is now considered to be an important risk factor for new or persistent obesity among women during the childbearing years. High gestational weight gain is the strongest predictor of maternal overweight or obesity following pregnancy. A growing body of evidence also suggests that both high and low gestational weight gains are independently associated with an increased risk of childhood obesity, suggesting that influences occurring very early in life are contributing to obesity onset. In response to these data, the United States Institute of Medicine (IOM) revised gestational weight gain guidelines in 2009 for the first time in nearly two decades. However, less than one-third of pregnant women achieve guideline-recommended gains, with the majority gaining above IOM recommended levels. To date, interventions to optimize pregnancy weight gains have had mixed success. In this paper, we summarize the evidence from human and animal studies linking over-nutrition and under-nutrition in pregnancy to maternal and child obesity. Additionally, we discuss published trials and ongoing interventions to achieve appropriate gestational weight gain as a strategy for obesity prevention in women and their children.
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影响因子：
120.7
作者：
Flegal, Katherine M.;Carroll, Margaret D.;Curtin, Lester R.
通讯作者：
Curtin, Lester R.
DOI：
10.3945/ajcn.110.008326
发表时间：
2011-06
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Fraser A;Tilling K;Macdonald-Wallis C;Hughes R;Sattar N;Nelson SM;Lawlor DA
通讯作者：
Lawlor DA
影响因子：
7.2
作者：
Bianco, AT;Smilen, TW;Lockwood, CJ
通讯作者：
Lockwood, CJ
影响因子：
7.7
作者：
Barker, DJP;Eriksson, JG;Osmond, C
通讯作者：
Osmond, C
影响因子：
8.9
作者：
Gardner, B.;Wardle, J.;Croker, H.
通讯作者：
Croker, H.