Higher vaccination rates predict reduction in SARS-CoV-2 transmission across the United States.
Higher vaccination rates predict reduction in SARS-CoV-2 transmission across the United States.
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DOI：
10.1007/s15010-022-01802-1
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发表时间：
2022-10
期刊：
影响因子：
7.5
通讯作者：
Au J
中科院分区：
文献类型：
--
作者：
Au J
2019年底/ 2020年初，严重急性呼吸综合征冠状病毒2 （SARS-CoV-2）开始在全球广泛扩散，造成了一场全球大流行和健康危机。尽管在大流行发生大约一年后，公众可以获得疫苗，但围绕疫苗接种仍然存在很大的犹豫。一个关键的关切来自于关于在接种疫苗者中出现突破性感染的报告，这些报告显示出与未接种疫苗者相当的峰值病毒载量水平，这使人们对疫苗预防传播的能力产生了质疑。因此，那些自身严重并发症风险较低的年轻健康个体，没有什么动力去接种一种他们不相信能保护周围其他人的疫苗。为了解决这一重要问题，本研究旨在评估疫苗接种率与未接种疫苗人群中SARS-CoV-2传播减少的关联程度。2021年6月至9月在美国进行了一项观察性研究。获得各州2019冠状病毒病（COVID-19）的疫苗接种率和发病率，以及一些重要的控制变量。根据各州的疫苗接种率，使用面板数据回归来预测未接种疫苗的发病率。在充分接种疫苗的个人比例较高的国家，在剩余未接种疫苗的人口中报告的新病例较少。这些数据进一步证明，COVID-19疫苗接种确实可以减缓SARS-CoV-2的传播，并且是社会武器库中将这场大流行置于我们身后的重要工具。在线版本包含补充材料，可在10.1007/s15010-022-01802-1获得。
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began proliferating widely throughout the world in late 2019/early 2020, creating a global pandemic and health crisis. Although vaccines became available to the public approximately 1 year after the onset of the pandemic, there still remains much hesitancy surrounding vaccination. One key concern comes from reports of breakthrough infections among the vaccinated that show comparable levels of peak viral load as the unvaccinated, calling into question the ability of vaccines to prevent transmission. Therefore young, healthy individuals who are at low risk of serious complications themselves have little incentive to receive a vaccine that they are not convinced will protect others around them. To address this important concern, this study aimed to evaluate the extent to which vaccination rates are associated with reduced SARS-CoV-2 transmission among the unvaccinated population. An observational study was conducted in the United States of America throughout the months of June through September, 2021. Vaccination rate and incidence of coronavirus disease 2019 (COVID-19) were obtained for each state, along with a number of important control variables. Panel data regression was used to predict incidence among the unvaccinated based on each state’s vaccination rate. States with a higher proportion of fully vaccinated individuals reported fewer new cases among the remaining unvaccinated population. These data add to accumulating evidence that COVID-19 vaccinations can indeed slow the spread of SARS-CoV-2, and are an important tool in society’s arsenal to put this pandemic behind us. The online version contains supplementary material available at 10.1007/s15010-022-01802-1.
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影响因子：
56.9
作者：
Prunas, Ottavia;Warren, Joshua L.;Crawford, Forrest W.;Gazit, Sivan;Patalon, Tal;Weinberger, Daniel M.;Pitzer, Virginia E.
通讯作者：
Pitzer, Virginia E.
影响因子：
3.7
作者：
Mecenas P;Bastos RTDRM;Vallinoto ACR;Normando D
通讯作者：
Normando D
BNT162B2 mRNA COVID-19疫苗的安全性和功效。
DOI：
10.1056/nejmoa2034577
发表时间：
2020-12-31
期刊：
The New England journal of medicine
影响因子：
--
作者：
Polack FP;Thomas SJ;Kitchin N;Absalon J;Gurtman A;Lockhart S;Perez JL;Pérez Marc G;Moreira ED;Zerbini C;Bailey R;Swanson KA;Roychoudhury S;Koury K;Li P;Kalina WV;Cooper D;Frenck RW Jr;Hammitt LL;Türeci Ö;Nell H;Schaefer A;Ünal S;Tresnan DB;Mather S;Dormitzer PR;Şahin U;Jansen KU;Gruber WC;C4591001 Clinical Trial Group
通讯作者：
C4591001 Clinical Trial Group
影响因子：
4.4
作者：
Mahajan, Uma, V;Larkins-Pettigrew, Margaret
通讯作者：
Larkins-Pettigrew, Margaret
影响因子：
3.9
作者：
Clark, Tom S.;Linzer, Drew A.
通讯作者：
Linzer, Drew A.