Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy.
Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering microscopy.
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DOI:
10.1002/anie.201306234
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发表时间:
2013-12-02
影响因子:
16.6
通讯作者:
Cheng, Ji-Xin
中科院分区:
文献类型:
--
作者:
Wang, Ping;Li, Junjie;Wang, Pu;Hu, Chun-Rui;Zhang, Delong;Sturek, Michael;Cheng, Ji-Xin
Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Here we demonstrate a platform of hyperspectral stimulated Raman scattering microscopy for fast, quantitative and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.
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