Circadian rhythms in insect disease vectors.
Circadian rhythms in insect disease vectors.
复制标题
DOI：
10.1590/0074-0276130438
复制
发表时间：
2013
影响因子：
2.8
通讯作者：
Kyriacou CP
中科院分区：
文献类型：
--
作者：
Meireles-Filho AC;Kyriacou CP
由于地球的自转，从细菌到人类的生物体都是在可预测的日常环境周期中进化的。这种强大的选择压力产生了内源性生物钟，调节行为，生理和代谢的许多方面，预测和同步内部时间保持周期性环境的变化。在吸血昆虫媒介中，昼夜节律钟协调摄食活动，这对病原体传播的动力学非常重要。我们最近目睹了昆虫媒介物种生物钟分子研究的重大进展，巩固了多年来收集的行为数据，为野外生物钟的调节提供了见解。下一代测序技术将促进物种间和物种内载体基因组/转录组的研究，并阐明在野外和实验室中观察到的适应性昼夜节律表型的一些物种特异性模式。在本次评论中，我们将探讨这些最新发现，并尝试确定需要进一步调查的潜在领域。
Organisms from bacteria to humans have evolved under predictable daily environmental cycles owing to the Earth’s rotation. This strong selection pressure has generated endogenous circadian clocks that regulate many aspects of behaviour, physiology and metabolism, anticipating and synchronising internal time-keeping to changes in the cyclical environment. In haematophagous insect vectors the circadian clock coordinates feeding activity, which is important for the dynamics of pathogen transmission. We have recently witnessed a substantial advance in molecular studies of circadian clocks in insect vector species that has consolidated behavioural data collected over many years, which provided insights into the regulation of the clock in the wild. Next generation sequencing technologies will facilitate the study of vector genomes/transcriptomes both among and within species and illuminate some of the species-specific patterns of adaptive circadian phenotypes that are observed in the field and in the laboratory. In this review we will explore these recent findings and attempt to identify potential areas for further investigation.
登录
查看更多内容
影响因子：
11.3
作者：
Baker CL;Loros JJ;Dunlap JC
通讯作者：
Dunlap JC
影响因子：
1.1
作者：
Barrozo, RB;Schilman, PE;Lazzari, CR
通讯作者：
Lazzari, CR
影响因子：
2.2
作者：
Barrozo, RB;Minoli, SA;Lazzari, CR
通讯作者：
Lazzari, CR
影响因子：
4.4
作者：
Dillon, Rod J.;Ivens, Al C.;Churcher, Carol;Holroyd, Nancy;Quail, Michael A.;Rogers, Matthew E.;Soares, M. Bento;Bonaldo, Maria F.;Casavant, Thomas L.;Lehane, Mike J.;Bates, Paul A.
通讯作者：
Bates, Paul A.
影响因子：
56.9
作者：
Darlington, TK;Wager-Smith, K;Kay, SA
通讯作者：
Kay, SA