Sex ratio adjustment and kin discrimination in malaria parasites.
Sex ratio adjustment and kin discrimination in malaria parasites.
复制标题
DOI：
10.1038/nature06954
复制
发表时间：
2008-05-29
期刊：
影响因子：
64.8
通讯作者：
Gardner, Andy
中科院分区：
文献类型：
--
作者：
Reece, Sarah E.;Drew, Damien R.;Gardner, Andy
疟疾寄生虫和相关的顶复门是人类、伴侣动物、牲畜和野生动物的一些最严重的传染病的病原体。这些寄生虫必须经过有性生殖才能从脊椎动物宿主传播到媒介，它们的性别比例一直偏向雌性。性别分配理论是进化生物学的基石，它在解释多细胞生物中雌性偏向的性别比例方面非常成功，但在应用于疟疾寄生虫时却存在争议。在这里，我们表明，正如理论预测的那样，性别比是一个重要的健身决定性状和疟原虫chabaudi寄生虫调整其性别分配响应不相关的同种的存在。这表明，夏氏疟原虫利用亲属歧视来评估其感染的遗传多样性，并根据环境线索调整其行为。疟疾寄生虫提供了一种新的方法来检验进化论，并支持达尔文方法的普遍性和力量。
Malaria parasites and related Apicomplexans are the causative agents of the some of the most serious infectious diseases of humans, companion animals, livestock and wildlife. These parasites must undergo sexual reproduction to transmit from vertebrate hosts to vectors, and their sex ratios are consistently female-biased. Sex allocation theory, a cornerstone of evolutionary biology, is remarkably successful at explaining female-biased sex ratios in multicellular taxa, but has proved controversial when applied to malaria parasites. Here we show that, as predicted by theory, sex ratio is an important fitness-determining trait and Plasmodium chabaudi parasites adjust their sex allocation in response to the presence of unrelated conspecifics. This suggests that P. chabaudi parasites use kin discrimination to evaluate the genetic diversity of their infections, and they adjust their behaviour in response to environmental cues. Malaria parasites provide a novel way to test evolutionary theory, and support the generality and power of a darwinian approach.
登录
查看更多内容
影响因子：
9.6
作者：
Ferguson, DJP
通讯作者：
Ferguson, DJP
影响因子：
2.4
作者：
JANSE, CJ;MONS, B;VANDERKAAY, HJ
通讯作者：
VANDERKAAY, HJ
DOI：
10.1073/pnas.0508871102
发表时间：
2005-11-29
影响因子：
11.1
作者：
Razakandrainibe, FG;Durand, P;Renaud, F
通讯作者：
Renaud, F
影响因子：
56.9
作者：
HERRE, EA
通讯作者：
HERRE, EA
影响因子：
3.3
作者：
Mackinnon, MJ;Read, AF
通讯作者：
Read, AF