Cognitive deficits of mild dementia:A comparison between dementia of the Alzheimer's type and vascular dementia
Cognitive deficits of mild dementia:A comparison between dementia of the Alzheimer's type and vascular dementia
复制标题
轻度痴呆的认知缺陷：阿尔茨海默型痴呆与血管性痴呆的比较
DOI：
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发表时间：
1998
影响因子：
11.9
通讯作者：
M. Sugishita
中科院分区：
文献类型：
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作者：
O. Matsuda;M. Saito;M. Sugishita
本研究旨在检测11例轻度痴呆的阿尔茨海默型痴呆(DAT)、5例伴多发皮质下腔隙梗死(VDS)的血管性痴呆和7例伴广泛脑白质损害(VDW)的血管性痴呆患者的认知功能障碍，并与23例非痴呆者进行比较。采用韦氏记忆量表日文版(WMS-R)和韦氏成人智力量表日文版(WAIS-R)评定记忆、注意力、抽象思维和视觉空间功能。与正常老年人相比，三组痴呆组在记忆和抽象思维方面均有明显的损害。然而，在注意力(即从WMS-R向后的心理控制和视觉记忆广度)和视觉空间功能(即来自WAIS-R的物体组装)的多项测试中，DAT组和VDS组之间的成绩有显著差异，其中VDS组的成绩比DAT组差。这项研究表明，在轻度痴呆阶段，DAT患者在注意力和视觉空间功能方面几乎没有问题，而VDS患者在这些认知能力上存在损害。
Abstract This study was designed to examine the profiles of cognitive deficits in 11 mildly demented patients with dementia of Alzheimer's type (DAT), five with vascular dementia with multiple subcortical lacunar infarcts (VDS), and seven with vascular dementia with extensive white matter lesions (VDW) in comparison with 23 aged individuals without dementia. Memory, attention, abstract thinking, and visuospatial function were assessed using the Japanese translation of the Wechsler Memory Scale‐Revised (WMS‐R) and the Japanese version of the Wechsler Adult Intelligence Scale‐Revised (WAIS‐R). Compared with normal aged individuals, three dementia groups were significantly impaired in the memory and abstract thinking. However, the performances on several tests on attention (i.e. Mental Control and Visual Memory Span Backward from WMS‐R) and visuospatial function (i.e. Object Assembly from WAIS‐R) differed significantly between the DAT and VDS groups, with VDS being the worst in terms of performance than was DAT. This study suggests that, in the mildly demented stage, the patients with DAT have few problems in the attention and visuospatial function, but those with VDS have impairments in these cognitive abilities.
影响因子：
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作者：
WELSH, KA;BUTTERS, N;HEYMAN, A
通讯作者：
HEYMAN, A